Risk factors and prognosis of adult-onset post-pump chorea

Ahn, Jong Hyeon; Song, Joomee; Choi, Inyoung; Youn, Jinyoung; Cho, Jin Whan

doi:10.1016/j.jns.2021.117328

Cited by 3 publications

(8 citation statements)

References 18 publications

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“…62 Risk factors can be young age (children), prolonged duration of cardiopulmonary bypass, longer duration of total circulatory arrest, hypothermia, and duration of aortic clamping. 60,63 The proposed mechanism is cerebral vasoconstriction due to hypocapnia and alkalosis during rewarming and increased blood viscosity. Hypothermia can also result in marked cerebral vasoconstriction leading to ischemic insult.…”

Section: Cardiopulmonary Bypassmentioning

confidence: 99%

“…However, initial MRI signal changes in the caudate and putamen have been associated with a poor outcome. 60…”

Section: Cardiopulmonary Bypassmentioning

confidence: 99%

“…This entity was first described in 1960 [ 58 ], and the incidence of post-pump chorea varies between 1–18 [ 59 ]. This is a rare entity, as evidenced by a recent study by Ahn et al [ 60 ], who identified 2 patients with adult-onset post-pump chorea out of 5,338 adults who underwent cardiopulmonary bypass. Although more common in children, it may be seen in adults following pulmonary endarterectomy, aortic arch and valve replacement surgeries [ 61 ].…”

Section: Post-surgical Movement Disordersmentioning

confidence: 99%

“…Apart from generalized chorea, orofacial dyskinesia, dysphagia, loss of tone and dysarthria can occur [ 62 ]. Risk factors can be young age (children), prolonged duration of cardiopulmonary bypass, longer duration of total circulatory arrest, hypothermia, and duration of aortic clamping [ 60 , 63 ].…”

Section: Post-surgical Movement Disordersmentioning

confidence: 99%

“…No differences in age, sex or surgical findings were observed in adults with post-pump chorea who had a good outcome versus those who had a bad outcome. However, initial MRI signal changes in the caudate and putamen have been associated with a poor outcome [ 60 ].…”

Section: Post-surgical Movement Disordersmentioning

confidence: 99%

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Movement Disorders Associated With Radiotherapy and Surgical Procedures

Surisetti¹,

Prasad²,

Holla

et al. 2023

JMD

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Occasionally, movement disorders can occur following interventional procedures including but not limited to radiotherapy, dental procedures, and cardiac, cerebral and spinal surgeries. The majority of these disorders tend to be unexpected sequelae with variable phenomenology and latency, and they can often be far more disabling than the primary disease for which the procedure was performed. Owing to poor knowledge and awareness of the problem, delays in diagnosing the condition are common, as are misdiagnoses as functional movement disorders. This narrative review discusses the phenomenology, pathophysiology, and potential treatments of various movement disorders caused by interventional procedures such as radiotherapy and neurological and non-neurological surgeries and procedures.

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Section: Cardiopulmonary Bypassmentioning

confidence: 99%

“…However, initial MRI signal changes in the caudate and putamen have been associated with a poor outcome. 60…”

Section: Cardiopulmonary Bypassmentioning

confidence: 99%

Section: Post-surgical Movement Disordersmentioning

confidence: 99%

Section: Post-surgical Movement Disordersmentioning

confidence: 99%

Section: Post-surgical Movement Disordersmentioning

confidence: 99%

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Movement Disorders Associated With Radiotherapy and Surgical Procedures

Surisetti¹,

Prasad²,

Holla

et al. 2023

JMD

View full text Add to dashboard Cite

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Chorea

Frucht,

Termsarasab

2024

Movement Disorders Phenomenology

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Diagnostic Uncertainties: Chorea

Cincotta

Walker

2023

Semin Neurol

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Chorea is a hyperkinetic movement disorder with a multitude of potential etiologies, both acquired and inherited. Although the differential diagnosis for new-onset chorea is extensive, there are often clues in the history, exam, and basic testing that can help to narrow the options. Evaluation for treatable or reversible causes should take priority, as rapid diagnosis can lead to more favorable outcomes. While Huntington's disease is most common genetic cause of chorea, multiple phenocopies also exist and should be considered if Huntington gene testing is negative. The decision of what additional genetic testing to pursue should be based on both clinical and epidemiological factors. The following review provides an overview of the many possible etiologies as well as a practical approach for a patient presenting with new-onset chorea.

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Risk factors and prognosis of adult-onset post-pump chorea

Cited by 3 publications

References 18 publications

Movement Disorders Associated With Radiotherapy and Surgical Procedures

Movement Disorders Associated With Radiotherapy and Surgical Procedures

Chorea

Diagnostic Uncertainties: Chorea

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