Risk factors and characteristics of lesions of the cardiovascular system in young aged patients with psoriasis (547.2)

Abstract

To study lipid metabolism,as well as the identification of risk factors,the characteristics of the cardiovascular system lesions in young aged patients with psoriasis. It was found in clinical and epidemiological study that among patients with psoriasis most men were ‐ 61.1%, women ‐ 38.9%. Mean age ‐ 46,4±2,3years. In the study of the spectrum the concomitant somatic pathology in adult patients 61.3% was identified with underlying diseases. In patients with severe psoriasis concomitant diseases were observed in 78.4% of patients, that is 1.3 times higher than in patients with psoriasis vulgaris and exudative. Lipid profile were as follows: hypercholesterolemia was diagnosed in 39.5% patients,74.4% patients, LDL cholesterol was above normal. Values of triglycerides (TG) averaged 1,82±0,15 mmol/l. In carrying out the cluster analysis between lipid profile and the main clinical and laboratory parameters in patients with psoriasis, revealed strong correlation rates (p<0.001) HDL with disease duration (r=‐0,95),with the affected area (r=‐0,83). In a study of the cardiovascular system in patients with psoriasis most often ‐ in 70% of cases met various cardiac arrhythmias. Signs of connective tissue dysplasia, namely, small malformations of the heart were detected in 25.6% patients. Hypertension was diagnosed in 9.3%, signs of peripheral atherosclerosis‐6.9% of the patients, ischemic heart disease‐4.7%.