Risk Factor-Related Lifestyle Habits of Patients With Laryngopharyngeal Reflux

Abstract

Objective The role of lifestyle habits in patients with laryngopharyngeal reflux disease (LPRD) is comparatively underexplored. We aim to examine the specific lifestyle habits in patients with LPRD. METHODS Systematic sampling was applied to select respondents aged 18 through 80 years in otorhinolaryngology-head and neck surgery (OHNS) clinics in Nan Fang Hospital during August 2017–July 2018, 1658 eligible participants were included by a systematic sampling method. Subjects with RSI score>13 were considered as LPRD patients. The risk of reflux symptoms was estimated and multivariate calculated as odds ratios in relation to exposure to tobacco smoking, alcohol, coffee, tea, carbonated drinks, chocolate, spicy food, night sleep time, dinner-to-bed time, subjective sleep quality, and physical exercise. Results There was a significant dose-response association between carbonated beverage and LPRD. Among people who had drinking carbonated drinks the odds ratio was 1.76 (OR 1.77, 95% CI 1.24–2.50, P = .002) compared with non-carbonated drinker. A similar positive association was found for poor subjective sleep quality and shorter night sleeping time, the odds ratio for reflux was 1.58 (95% CI 1.14 to 2.18) among those who always have poor subjective sleep quality compared with those whose have good subjective sleep quality. The odds ratio for reflux was 2.29 (95% CI 1.23–4.28, P = .015) among those who always sleep 3–5 hours every night compared with those who sleep more than 8 hours every night. Beyond that, we found high BMI may have a negative correlation with LPRD, the odds ratio for reflux was .61 (95% CI 0.39 to .95, P = .054) among those whose BMI >25 kg/m2 compared with those BMI ≤ 20 kg/m2. Conclusions Patients with LPRD may have certain lifestyle habits, avoid carbonated beverage, poor subjective sleep quality, and lack of sleep should be advised in treatment of LPRD.

Relationship between total free Sugars Consumption and Incidence of Laryngopharyngeal Reflux in Adolescents

“…Our study results indicated that 30 (14.3%) adolescents were overweight, 1 (0.5%) adolescent had obesity, and no significant association was found between BMI and LPR incidence (p = 0.094). Our study results differ from those of the study of Wang et al (10) showing that subjects with BMI >25 kg/m 2 had a 0.61-fold LPR risk than had subjects with BMI ≤ 20 kg/m 2 (OR= 0.61; 95% CI 0.39 -0.95, p = 0.054). Obesity is known to be related to gastroesophageal reflux disease, in that visceral fat synthesizes various cytokines that may lead to esophageal inflammation and damage to the esophageal mucosal barrier through refluxindependent mechanisms, such that the esophageal mucosa becomes particularly susceptible to GERD-induced injury.…”

“…(29) However, in this respect the results of LPR studies are conflicting. (6,10) Our study results showed statistically significant differences in free sugars consumption between the LPR negative and positive groups (p< 0.049). Our results are identical to those of the study of Li et al (5) where free sugars consumption significantly increased the risk of LPR 1.656 times after adjustment for multiple covariates (AOR =1.656; 95%CI = 2.516 -6.661, p=0.003).…”

“…LPR can be decreased by lifestyle interventions, such that in the prevention of LPR, determining its risk factors is essential. (7) Other factors that are linked to causative factors of LPR are among others age, (5,8,9) BMI, (10) sleep quality, (10) alcohol consumption, smoking, (6) and diet. (11) The World Health Organization (WHO) has coined the phrase "free sugars" to denote monoand disaccharides that have been added to "foods and beverages by the manufacturer, cook, or consumer".…”

Trattamento delle disfonie funzionali e organiche recidivanti: una review narrativa

“…In addition to pathological gastro-oesophageal or pharyngo-laryngeal conditions which may be associated or non-recognised, several other risk factors related to GERD and LPRD may play a key role in favouring chronic-recurrent clinical courses, even in case of thorough diagnostic approaches and adequate treatment regimens. These risk factors include: inadequate dietary regimens (lack of adherence to the Mediterranean diet); high consumption of specific foods (acid or with high protein or fat content); poor eating habits; tobacco smoke; alcohol abuse; obesity and overweight; sleep disorders; psychosocial distress 98 .…”

The Impact of Nutrition on the Onset, Course of the Disease and Quality of Life of Patients with Laryngopharyngeal Reflux

“…The food frequency questionnaire is commonly used to assess dietary habits in clinical studies and it estimates the frequency of consumption of beverages and foods ( 11 , 12 ). Lifestyle habits, including eating habits, vary in different countries and are often culturally conditioned ( 13 , 14 ). Therefore, eating habits should be studied separately for each region.…”