Abstract:To investigate whether 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (statin) use is associated with an increased risk of diabetes mellitus and hyperglycemia, we performed a nested case-control study using a postmarketing surveillance database in Japan. The database cohort included 26,849 cases of statin use and 5308 cases of other lipid-lowering drug use in patients with hyperlipidemia. Participants received at least 1 type of statin, had a clear medication history of statin use, and had no compli… Show more
“…In addition, long-term statin use on patients at high risk of diabetes onset causes significantly more diabetes onset 75) . According to post-marketing surveillance data, fatty liver and hyperuricemia are risk factors for diabetes onset 76) .…”
“…In addition, long-term statin use on patients at high risk of diabetes onset causes significantly more diabetes onset 75) . According to post-marketing surveillance data, fatty liver and hyperuricemia are risk factors for diabetes onset 76) .…”
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