Risk factor analysis of perioperative mortality after ruptured bleeding in hepatocellular carcinoma

Lin, Hui‐Ping; Lei, Liming; Zhu, Jing; Li, Guolin; Jun, Min

doi:10.3748/wjg.v20.i40.14921

Cited by 22 publications

(21 citation statements)

References 18 publications

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“…Thus, when patients are judged to be able to tolerate surgery, hepatic resection should be the first choice of treatment. Furthermore, a curative resection should be the objective as it was found to be the only independent prognostic factor in this study and in 3 other reports [11,12,15] . Regarding the treatment of patients with ruptured HCC, Yoshida et al [10] noted that prolonged survival was achieved in selected patients who had undergone liver resection.…”

Section: Discussionmentioning

confidence: 74%

An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma

et al. 2015

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Background/Aims: The prognosis of spontaneous rupture of hepatocellular carcinoma (HCC) remains unclear. We investigated the prognosis of patients with ruptured HCC based on the treatments and prognostic factors associated with long-term survival. Methods: The prognoses of 64 consecutive patients treated for ruptured HCC from 1986 to 2013 were analyzed according to their methods of treatment. The prognostic factors of 16 surgical patients were identified, and their overall survival (OS) and recurrence rates were compared to 1,157 surgical patients who underwent surgery for non-ruptured HCC. The surgical outcomes were also compared using a propensity score matching method. Results: Surgery was associated with a better OS. Curative resection was the only independent prognostic factor in surgical patients with ruptured HCC (p = 0.040). Although the OS of surgical patients with non-ruptured HCC was found to be significantly better than that of the patients with ruptured HCC, no significant difference in OS was observed after propensity score matching. Conclusion: A curative resection should be the objective of treatment, assuming the suitability of the patient's clinical condition. When the liver function reserve and tumor extension of patients with ruptured and non-ruptured HCC are similar, then their surgical outcomes may not be significantly different.

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Section: Discussionmentioning

confidence: 74%

An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma

et al. 2015

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“…Searching the reference list (snowball procedure) retrieved two additional articles. In total, 67 studies were deemed eligible and therefore included in the systematic review …”

Section: Resultsmentioning

confidence: 99%

Management, outcomes, and prognostic factors of ruptured hepatocellular carcinoma: A systematic review

Moris

Chakedis

Sun

et al. 2017

Journal of Surgical Oncology

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Ruptured hepatocellular (rHCC) is a rare but life-threatening presentation that often requires acute intervention. In this systematic review we identified 67 eligible studies reporting on 4941 patients with rHCC. Here we present the treatment approaches for the management of rHCC both in the acute setting with regards to management of hemorrhage, as well long-term with regards to oncological treatment.

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“…[3–10] With improvements in patient selection, surgical techniques, and postoperative care, the mortality rate has improved dramatically in recent decades. [3,11–13] The unexpected occurrence of death after the operation, however, is still catastrophic to both the patients’ family and surgeon. As a result, the identification of potential risk factors for mortality before operation is of paramount importance.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for early mortality after hepatectomy for hepatocellular carcinoma

et al. 2016

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Risk factor analysis of perioperative mortality after ruptured bleeding in hepatocellular carcinoma

Abstract: Radical resection and TAE therapy would achieve better results in carefully selected ruptured hepatocellular tumours.

Cited by 22 publications

References 18 publications

An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma

An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma

Management, outcomes, and prognostic factors of ruptured hepatocellular carcinoma: A systematic review

Risk factors for early mortality after hepatectomy for hepatocellular carcinoma

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