The high rate of injuries occurring in agricultural activities is of major concern in most countries, despite the ever-increasing efforts made at normative levels. In particular, the use of agricultural tractors is recognized as the most hazardous activity for farmers due to the large number of fatalities occurring every year. The aim of the present study was to investigate the recent developments in research activities dealing with tractor safety. For this purpose, a systematic literature review was carried out, taking into account engineering journal papers appearing in Scopus in the 2009–2019 period and focusing on tractor safety. As a result, 79 documents were selected and analyzed based on both their type (e.g., conceptual or empirical studies) and specific targets. They were then classified and discussed in accordance with a reference framework representing the main issues of agricultural tractor safety: mechanical hazards, protective devices, command and control, other hazards, ergonomics, information, conformity, and user behavior. The results of this analysis brought to light the need for a more human-centered approach when dealing with tractor safety. In addition, the lack of a reliable framework of technical standards was also stressed. Overall, despite the limitations due to the selection criteria, this study represents the first systematic literature review depicting the status of tractor safety in the engineering field, providing a basis for further research on the emerging themes outlined.