Risk Criteria and Prognostic Factors for Predicting Recurrences After Resection of Primary Gastrointestinal Stromal Tumor

Abstract

The risk criteria for assessing the natural course of primary GISTs were validated, but additional independent prognostic factors-primary tumor location and sex--were also identified.

Gastric gastrointestinal stromal tumor with incomplete duplication cyst – a case with possibility of neoplasia in fetal-period malformed tissues

“…Similar clinical symptoms can be caused by many different gastric tumors, especially usual cancers.IntheexperienceofthePolishGastrointestinal TumorWorkingGroupbleedingfromulceratedgastricGISTsorrupturedGISTsisafrequentandtypical complication in clinical outcomes [6,7]. Like other pastcasesofGISTs,thepresentcaseproceededwith massivegastricbleedingandrequiredanurgentlaparotomywithlocaltumorresection.Rarely,described cases of gastric bleeding are complex and might be connectedwithanothertypesofgastrictumorsbesides GISTsorGDCoccurringincidentally,simultaneously also with other kind of cancer.…”

A Retrospective Study of the Incidence of GIST in Scotland from 1995 to 1999

“…Similarly a decline in non-GIST cases has been noted reflecting improved diagnostic accuracy [19]. The increasing use of mutational analysis in diagnosis of GIST will increase the accuracy of GIST incidence figures [17]. Table 3: Comparison with other studies of GIST incidence.…”

“…Unlike the NIH criteria this is more scientifically robust as it is based on a series of over 1900 GISTs and has been accepted as the principle prognostic system by the European Society of Medical Oncologists (ESMO) and the National Comprehensive Cancer Network. Its main difference is that it includes the addition of tumour site as a prognostic factor which has been further validated by subsequent studies [16,17]. Our study aims to validate overall survival using the AFIP criteria.…”

Gastrointestinal Stromal Tumors

“…When the tumor attaches to other organs, en bloc resection is appropriate. Intraperitoneal rupture or bleeding is associated with a high risk of postoperative recurrence of nearly 100% [43, 75,76]. Therefore, it is of critical importance that the GIST, which is soft and fragile in nature, does not rupture intraoperatively demanding special care while handling the tumor.…”