2018
DOI: 10.1002/ieam.4096
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Risk‐based approach in the revised European Union drinking water legislation: Opportunities for bioanalytical tools

Abstract: A plethora of in vitro bioassays are developed in the context of chemical risk assessment and clinical diagnostics to test effects on different biological processes. Such assays can also be implemented in effect-based monitoring (EBM) of (drinking) water quality alongside chemical analyses. Effects-based monitoring can provide insight into risks for the environment and human health associated with exposure to (unknown) complex, low-level mixtures of micropollutants, which fits in the risk-based approach that w… Show more

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Cited by 38 publications
(13 citation statements)
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“…Both advancements in microbial analytical methods and a move towards risk-based methods (as opposed to the traditional travel time-based methods) in drinking water management require a closer integration of hydrology with hydrogeochemistry and microbiology (e.g. Mayer et al 2018, Dingemans et al 2019.…”
Section: Interfaces In Hydrologymentioning
confidence: 99%
See 1 more Smart Citation
“…Both advancements in microbial analytical methods and a move towards risk-based methods (as opposed to the traditional travel time-based methods) in drinking water management require a closer integration of hydrology with hydrogeochemistry and microbiology (e.g. Mayer et al 2018, Dingemans et al 2019.…”
Section: Interfaces In Hydrologymentioning
confidence: 99%
“…Second, new topics seem to emerge where hydrology can play a more important role such as contaminants of emerging concern, microbial pathogens, or, more generally, the topic of water and health (e.g. Mayer et al 2018, Dingemans et al 2019, as well as spatial problems such as the interaction of migration and water issues. Third, the questions are broadened in terms of their spatial scales.…”
Section: Water and Societymentioning
confidence: 99%
“…Current drinking water regulation regarding chemical contaminants is in most countries, including the European Union, based on defined maximum concentration levels of a very limited number of chemicals or groups of chemicals [2]. There is, however, a substantial body of scientific literature showing that these well-known environmental pollutants can only explain a relatively small proportion of the observed toxicity in water samples, especially for toxicity endpoints such as reactive toxicity, xenobiotic metabolism and oxidative stress [3][4][5][6][7]. For some of these endpoints, the well-known environmental pollutants can only explain as little as 0.1-5% of the observed toxicity, implying that up to 99.9% of the toxicity is caused by unknown chemicals or mixture effects [3,4].…”
Section: Introductionmentioning
confidence: 99%
“…It is expected that a risk-based monitoring workflow for water reuse for irrigation can be based on the available technologies currently in use for drinking water purposes [47,54]. These can be complemented with bioanalytical tools that give information on the integrated effect of mixtures of chemicals related to a specific health effect [55,56]. By referring to a list of EU legislations on microbial and chemical risks from which requirements and obligations are also to be taken into account, many additional water quality requirements are indirectly included in the proposed regulation.…”
Section: Health and Safety Including Water Treatmentmentioning
confidence: 99%