Risk Assessment of Baby Powder Exposure through Inhalation

Moon, Min Chaul; Park, Jung Duck; Choi, Byung Soon; Park, So Young; Kim, Dong Won; Chung, Yong Hyun; Hisanaga, Naomi; Yu, Il Je

doi:10.5487/tr.2011.27.3.137

Cited by 19 publications

(16 citation statements)

References 9 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The initial literature search returned 590 results. In total, seven of these studies contained measured airborne concentration data associated with the consumer use of cosmetic talcum powder products (Anderson, Sheehan, Kalmes, & Griffin, ; Aylott, Byrne, Middleton, & Roberts, ; Dement, Shuler, & Zumwalde, ; Gordon, Fitzgerald, & Millette, ; Hildick‐Smith, ; Moon et al., ; Russell, Merz, Sherman, & Sivertson, ). Of the studies identified, four studies presented measured airborne dust concentration data and two presented measured airborne fiber concentration data.…”

Section: Resultsmentioning

confidence: 99%

“…(); H 1976, Hildick‐Smith (); M 2011, Moon et al. (); G 2014, Gordon et al. (); An 2017, Anderson et al.…”

Section: Resultsmentioning

confidence: 99%

“…(), and Moon et al. () reported respirable talc particle exposures to an infant generated from the application of cosmetic talcum powder during diapering activities. Sample durations ranged from 0.35 to 5 minutes with powdering times from 15 to 60 seconds.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Potential Airborne Asbestos Exposure and Risk Associated with the Historical Use of Cosmetic Talcum Powder Products

Burns¹,

Barlow²,

Banducci³

et al. 2019

Risk Analysis

View full text Add to dashboard Cite

Over time, concerns have been raised regarding the potential for human exposure and risk from asbestos in cosmetic-talc-containing consumer products. In 1985, the U.S. Food and Drug Administration (FDA) conducted a risk assessment evaluating the potential inhalation asbestos exposure associated with the cosmetic talc consumer use scenario of powdering an infant during diapering, and found that risks were below levels associated with background asbestos exposures and risk. However, given the scope and age of the FDA's assessment, it was unknown whether the agency's conclusions remained relevant to current risk assessment practices, talc application scenarios, and exposure data. This analysis updates the previous FDA assessment by incorporating the current published exposure literature associated with consumer use of talcum powder and using the current U.S. Environmental Protection Agency's (EPA) nonoccupational asbestos risk assessment approach to estimate potential cumulative asbestos exposure and risk for four use scenarios: (1) infant exposure during diapering; (2) adult exposure from infant diapering; (3) adult exposure from face powdering; and (4) adult exposure from body powdering. The estimated range of cumulative asbestos exposure potential for all scenarios (assuming an asbestos content of 0.1%) ranged from 0.0000021 to 0.0096 f/cc-yr and resulted in risk estimates that were within or below EPA's acceptable target risk levels. Consistent with the original FDA findings, exposure and corresponding health risk in this range were orders of magnitude below upper-bound estimates of cumulative asbestos exposure and risk at ambient levels, which have not been associated with increased incidence of asbestos-related disease.

show abstract

Section: Resultsmentioning

confidence: 99%

“…(); H 1976, Hildick‐Smith (); M 2011, Moon et al. (); G 2014, Gordon et al. (); An 2017, Anderson et al.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Potential Airborne Asbestos Exposure and Risk Associated with the Historical Use of Cosmetic Talcum Powder Products

Burns¹,

Barlow²,

Banducci³

et al. 2019

Risk Analysis

View full text Add to dashboard Cite

show abstract

“…As discussed in Section 4.1.2 “Effect of Particle and Fiber Settling on Cosmetic Talc Cumulative Exposure Potential” and Section 4.1.3 “Airborne Fiber Concentrations and the Association with Bulk Concentrations”, the available measured data regarding the relationship between bulk asbestos content and airborne fiber concentrations are consistent with the results of the analysis in our paper (Addison, Davies, Robertson, & Willey, ). For example, as reported in other peer‐reviewed published literature, the results of workplace airborne concentration data for talcum powder containing less than 0.1% asbestos were estimated to be 0.01 fibers/cc (Mattenklott, ; Moon et al., ). The airborne concentration values described in Mattenkott, are within the range of the estimated air concentrations associated with adult use of talcum powder products reported in Table II of our paper.…”

Section: Recalculation Of Exposurementioning

confidence: 89%

“…However, he has only referenced two studies, Gordon, Fitzgerald, & Millette, , as well as an unpublished report by Longo and colleagues in 2017. Our data‐driven assessment was based on seven studies of cosmetic talc airborne exposure fiber and dust concentrations, including the single published study mentioned by Dr. Finkelstein (i.e., Gordon et al, ) (Anderson, Sheehan, Kalmes, & Griffin, ; Aylott, Byrne, Middleton, & Roberts, ; Dement, Shuler, & Zumwalde, ; Gordon, Fitzgerald, & Millette, ; Hildick‐Smith, ; Moon et al, ; Russell, Merz, Sherman, & Sivertson, ). The report by Longo et al.…”

Section: Studies With Direct Measurementsmentioning

confidence: 99%

Response to Letter to the Editor

Burns¹,

Barlow²,

Banducci³

et al. 2019

Risk Analysis

View full text Add to dashboard Cite

We appreciate Dr. Finkelstein's interest in our paper, however, he has misinterpreted some key points of our publication. The purpose of our assessment was to take a conservative regulatory approach in the interest of public health to assess the potential for airborne asbestos exposure associated with consumer use of cosmetic talc under typical use scenarios. We reject Dr. Finkelstein's assertion that we have dramatically underestimated exposure and risk associated with the typical use of cosmetic talcum powder products. As stated in our study, we relied on the approach used by the FDA in their own 1985 risk assessment of cosmetic talcum powder to determine the airborne fiber content of cosmetic talc dust during application; the FDA referenced their own testing data in this analysis and characterized it as a "worst case". Furthermore, Dr. Finkelstein's conclusions are not supported by the wealth of publicly available data on the subject.

show abstract

Talc

Ierardi,

Burns,

Bernstein

2023

Patty's Toxicology

View full text Add to dashboard Cite

Talc (Mg 3 Si 4 O 10 (OH) 2 ), a hydrated magnesium silicate, consists of magnesium (Mg), silicon and oxygen (SiO 2 , silica), and water. Inhalation of talc – in particular, cosmetic‐grade talc – has been implicated as a causal agent of mesothelioma among consumers due to the potential presence of trace levels of asbestos. Over the past several decades, the scientific community has taken several steps to evaluate this hypothesis from a human health risk assessment perspective. This chapter presents a summary of the available animal toxicology, epidemiology, and exposure data related to this topic. The focus of this chapter is primarily on cosmetic‐grade talc, as the relatively pure talc used in cosmetic applications provides the best source of data for evaluating the health effects of the mineral itself. The current weight of evidence suggests that relatively pure talc, which is used in cosmetics, as well as other consumer products, does not pose a carcinogenic health risk upon inhalation.

show abstract

Risk Assessment of Baby Powder Exposure through Inhalation

Cited by 19 publications

References 9 publications

Potential Airborne Asbestos Exposure and Risk Associated with the Historical Use of Cosmetic Talcum Powder Products

Potential Airborne Asbestos Exposure and Risk Associated with the Historical Use of Cosmetic Talcum Powder Products

Response to Letter to the Editor

Talc

Contact Info

Product

Resources

About