Risk and outcome analysis of 1832 consecutively excised basal cell carcinoma's in a tertiary referral plastic surgery unit

Malik, Vinod; Goh, King Soon; Leong, Sum; Tan, Angeline; Downey, David; O’Donovan, David

doi:10.1016/j.bjps.2010.01.016

Cited by 35 publications

(24 citation statements)

References 39 publications

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“…These results are extremely high as compared to what is reported in the literature. Studies report frequency of incomplete excision ranging from 3–20% [1, 14, 15, 21]. A four millimeter excision margin is currently recommended for small, well demarcated BCC's as this gives a complete excision rate of approximately 95% [22].…”

Section: Discussionmentioning

confidence: 99%

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Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

Janjua

Qureshi

2012

Journal of Skin Cancer

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Objective. To analyze the pattern of presentation of basal cell carcinoma (BCC) and margin status for excised specimens in the head and neck region. Study Design. Retrospective cross-sectional. Duration of Study. January 2009 to December 2011. Methodology. The database of the pathology department was searched to identify records of all malignant skin tumors that underwent standard excision with margins. Out of these records, tumors with a diagnosis of BCC in the head and neck region were retrieved and separated. Age, gender, anatomic location, pattern of tumor, and margin status were noted. Results. A total of 171 cases of BCC from various sites of head and neck were retrieved. Male to female ratio was 1.4 : 1. The age ranged from 22 to 90 years. Seventy-six cases presented on right side, 79 on left, and 16 were in the midline. Most common anatomical site was the nose followed by the cheek. Nodular lesions were the most common (46.2%) followed by pigmented variety (18.7%). Margins were clear in 77 (45.1%) cases, involved in 86 (50.2%) cases, and close in 8 (4.7%) cases. Conclusion. Nose was the most common site followed by the cheek. Nodular and pigmented varieties were the most frequent and margins were involved in more than fifty percent of the cases.

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Section: Discussionmentioning

confidence: 99%

“…Jacob Arthur in Dublin in 1827 first coined the term “rodent ulcer” to describe what we now know as a basal cell carcinoma (BCC) [1]. It takes its name from the resemblance of the epithelial tumor cells to normal basal cells of the skin.…”

Section: Introductionmentioning

confidence: 99%

Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

Janjua

Qureshi

2012

Journal of Skin Cancer

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“…Reported rates of incomplete excision after routine excision ranges from 1.9% to 16% (Table 1). [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] In a recent study by Leibovitch and colleagues of Mohs micrographic surgery (MMS) in Australia, 11,127 BCC cases were referred for MMS; the reason for referral in 33.1% cases was tumor recurrence. 17 Factors contributing to incomplete excision include difficulty in establishing clinical margins, especially when prior cryotherapy has destroyed tissue architecture, and in certain histologic subtypes with poorly defined macroscopic borders.…”

Section: Ncomplete Excision Of Basal Cell Carcinoma (Bcc)mentioning

confidence: 99%

Incompletely Excised Basal Cell Carcinoma: Residual Tumor Rates at Mohs Re-Excision

Palmer

Wilson

2013

Dermatologic Surgery

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Immediate re-excision using MMS is recommended for treatment of incompletely excised BCC because the majority of cases have histologically detectable BCC. Watch and wait advice could lead to significant morbidity because recurrence may necessitate more extensive closures and costs. Long-term follow-up is recommended. It is important to conduct self-audits of incomplete excisions and follow up these patients.

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“…Jacob Arthurin 1827 first coined the term "rodent ulcer" to describe what we now know as a basal cell carcinoma (BCC) [1]. It is the most common cutaneous malignancy worldwide, accounting for 65-75% of all skin cancers.…”

Section: Introductionmentioning

confidence: 99%

A study of basal cell carcinoma in South Asians for risk factor and clinicopathological characterization: A hospital based study

2015

Journal of the American Academy of Dermatology

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Objectives. Although the incidence of skin cancers in India (part of South Asia) is low, the absolute number of cases may be significant due to large population. The existing literature on BCC in India is scant. So, this study was done focusing on its epidemiology, risk factors, and clinicopathological aspects. Methods. A hospital based cross-sectional study was conducted in Punjab, North India, from 2011 to 2013. History, examination and histopathological confirmation were done in all the patients visiting skin department with suspected lesions. Results. Out of 36 confirmed cases, 63.9% were females with mean ± SD age being 60.9 ± 14.2 years. Mean duration of disease was 4.7 years. Though there was statistically significant higher sun exposure in males compared to females ( value being 0.000), BCC was commoner in females, explainable by intermittent sun exposure (during household work in the open kitchens) in women. Majority of patients (88.9%) had a single lesion. Head and neck region was involved in 97.2% of cases, with nose being the commonest site (50%) with nodular/noduloulcerative morphology in 77.8% of cases. Pigmentation was evident in 22.2% of cases clinically. Nodular variety was the commonest histopathological variant (77.8%).Conclusions. This study highlights a paradoxically increasing trend of BCC with female preponderance, preferential involvement of nose, and higher percentage of pigmentation in Indians.

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Risk and outcome analysis of 1832 consecutively excised basal cell carcinoma's in a tertiary referral plastic surgery unit

Cited by 35 publications

References 39 publications

Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

Basal Cell Carcinoma of the Head and Neck Region: An Analysis of 171 Cases

Incompletely Excised Basal Cell Carcinoma: Residual Tumor Rates at Mohs Re-Excision

A study of basal cell carcinoma in South Asians for risk factor and clinicopathological characterization: A hospital based study

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