Risen from the dead: A case of the Lazarus phenomenon—With considerations on the termination of treatment following cardiac arrest in a prehospital setting

Krarup, Niels; Kaltoft, Anne; Lenler-Petersen, P

doi:10.1016/j.resuscitation.2010.06.010

Cited by 16 publications

(6 citation statements)

References 5 publications

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“…Return of myocardial function following Termination of Resuscitation (TOR) Myocardial reperfusion due to spontaneous dislodging of endovascular plaque from a coronary artery [7,10,38]. Might also possibly allow spontaneous defibrillation in refractory VF [8,23,60].…”

Section: Spontaneousmentioning

confidence: 99%

Autoresuscitation (Lazarus phenomenon) after termination of cardiopulmonary resuscitation - a scoping review

Gordon

Pasquier

Brugger

et al. 2020

Scand J Trauma Resusc Emerg Med

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Background: Autoresuscitation describes the return of spontaneous circulation after termination of resuscitation (TOR) following cardiac arrest (CA). We aimed to identify phenomena that may lead to autoresuscitation and to provide guidance to reduce the likelihood of it occurring. Materials and methods: We conducted a literature search (Google Scholar, MEDLINE, PubMed) and a scoping review according to PRISMA-ScR guidelines of autoresuscitation cases where patients undergoing CPR recovered circulation spontaneously after TOR with the following criteria: 1) CA from any cause; 2) CPR for any length of time; 3) A point was reached when it was felt that the patient had died; 4) Staff declared the patient dead and stood back. No further interventions took place; 5) Later, vital signs were observed. 6) Vital signs were sustained for more than a few seconds, such that staff had to resume active care. Results: Sixty-five patients with ROSC after TOR were identified in 53 articles (1982-2018), 18 (28%) made a full recovery. Conclusions: Almost a third made a full recovery after autoresuscitation. The following reasons for and recommendations to avoid autoresuscitation can be proposed: 1) In asystole with no reversible causes, resuscitation efforts should be continued for at least 20 min; 2) CPR should not be abandoned immediately after unsuccessful defibrillation, as transient asystole can occur after defibrillation; 3) Excessive ventilation during CPR may cause hyperinflation and should be avoided; 4) In refractory CA, resuscitation should not be terminated in the presence of any potentially-treatable cardiac rhythm; 5) After TOR, the casualty should be observed continuously and ECG monitored for at least 10 min.

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Section: Spontaneousmentioning

confidence: 99%

Autoresuscitation (Lazarus phenomenon) after termination of cardiopulmonary resuscitation - a scoping review

Gordon

Pasquier

Brugger

et al. 2020

Scand J Trauma Resusc Emerg Med

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show abstract

“…Özellikle atropin, adrenalin, katekolaminlerin etkisinin geç ortaya çıkması da otoresüsitasyon ile ilişkilendirilmiştir (7,8,18,19).…”

Section: İlaçların Gecikmiş Etkisiunclassified

Lazarus Fenomeni

DOĞAN¹,

KILIBOZ²,

Karbeyaz³

2021

Osmangazi̇ Journal of Medicine

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Özet: Lazarus fenomeni, kardiyopulmoner resüsitasyon uygulamasının sonlandırılmasından ve resmi olarak hastanın öldüğünün kabul edilmesinden sonra, kendiliğinden spontan solunum ve dolaşımın geri dönmesi olarak tanımlanmaktadır. Lazarus fenomeni ile ilgili literatür, olgu sunumlarından ibaret olup, konuyla ilgili insidans çalışması olmadığı görülmektedir. Etiyolojisi tam olarak bilinmemekle birlikte çeşitli teoriler ileri sürülmektedir. İlaçların gecikmiş etkisi, hipervetilasyon, hipotermi, hipovolemi, hiperkalemi, alkaloz gibi durumlar lazarus fenomeni ile ilişkilendirilmiştir. Bu derlemede, lazarus fenomeni ile ilgili teorilerin sunulması, literatürdeki konu ile ilgili olguların incelenmesi ile lazarus fenomenin adli tıbbi yönünün değerlendirilmesi amaçlanmıştır.

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“…Krarup et al. 10 reported on one of the few cases of autoresuscitation with good neurological outcome. 2 It has been reported that survival with minimal neurological disability is possible after extra-corporeal membrane oxygenation (ECMO).…”

Section: Recoverymentioning

confidence: 99%

“…This mechanism, seemingly appropriate, is still difficult to completely accept. 5 Drugs namely, inotropes such as atropine, 10 adrenaline 10,11 have been reported to be administered during resuscitative efforts. Latency of catecholamine 6 action has also been proposed as a mechanism for the occurrence of return of spontaneous circulation (ROSC).…”

Section: Delayed Action Of Drugsmentioning

confidence: 99%

“…1,4,5 There has been a reported case of Lazarus phenomenon who went on to achieve a neurological recovery of 100%. 1 Krarup et al 10 reported on one of the few cases of autoresuscitation with good neurological outcome. 2 It has been reported that survival with minimal neurological disability is possible after extracorporeal membrane oxygenation (ECMO).…”

Section: Neurological Recoverymentioning

confidence: 99%

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The Lazarus phenomenon

Sahni

2016

JRSM Open

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The Lazarus phenomenon or the unassisted return of spontaneous circulation after cardiac arrest is a grossly underreported phenomenon in medical literature which essentially implies the ‘resurrection’ of an individual after cardiac arrest. Although there have been a handful of such cases reported, the clinical incidence and significance may be underestimated. Because of the presumed infrequency of this condition, there are no studies specifically researching Lazarus phenomenon in scientific literature. This review intends to systematically present current and past knowledge on this rare but definitive phenomenon. Research databases namely Google Scholar, Science Direct, Medline and PubMed were utilized. Only articles which identified cases where the return of spontaneous circulation occurred after cessation of Cardiopulmonary Resuscitation (CPR), and review articles on the entity were included. The mentioned databases were searched using the terms ‘Lazarus phenomenon’, ‘cardiopulmonary resuscitation’ and ‘return of spontaneous circulation’. A literature review was synthesised based on articles meeting the eligibility criteria to better understand the phenomenon of return of spontaneous circulation.

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Risen from the dead: A case of the Lazarus phenomenon—With considerations on the termination of treatment following cardiac arrest in a prehospital setting

Cited by 16 publications

References 5 publications

Autoresuscitation (Lazarus phenomenon) after termination of cardiopulmonary resuscitation - a scoping review

Autoresuscitation (Lazarus phenomenon) after termination of cardiopulmonary resuscitation - a scoping review

Lazarus Fenomeni

The Lazarus phenomenon

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