Rise of intraocular pressure in a caffeine test <i>versus</i> the water drinking test in patients with glaucoma

Tran, Tuan; Niyadurupola, Nuwan; O’Connor, Jeremy; Ang, Ghee Soon; Crowston, Jonathan G; Nguyen, Dan Q

doi:10.1111/ceo.12259

Cited by 16 publications

(7 citation statements)

References 34 publications

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“…14 Similarly, Ulas et al have shown that IOP elevation after WDT in healthy eyes occurs within the first 10 minutes and recovers quickly. 19 Tran et al reported mean peak IOP was highest at 45 minutes after water ingestion in patients with primary open-angle glaucoma (POAG), 20 whereas Hatanaka et al found that mean peak IOP was highest at 30 minutes in subjects with ocular hypertension and open-angle glaucoma. 21 It has been postulated that a more rapid return to baseline IOP following WDT may reflect an improved outflow facility.…”

Section: Interpreting the Resultsmentioning

confidence: 99%

Water drinking test in glaucoma management: a review of the literature

Khoo¹,

Cheng²,

Din³

2022

MyJO

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Purpose: To describe the methods of performing the water drinking test (WDT) and its applications in glaucoma management. Methods: This review is based on pertinent publications retrieved by a selective search in PubMed, supplemented by further articles chosen by the authors. Results: Intraocular pressure (IOP) changes throughout the day. IOP peak has been identified as a risk factor in glaucoma onset and progression. WDT is a simple stress test used by many researchers to elicit IOP peaks in assessing response to glaucoma treatments. Conclusions: Studies have shown the reproducibility and promising results of WDT in various pharmacological and surgical treatments of glaucoma. It is an important tool in glaucoma management.

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Section: Interpreting the Resultsmentioning

confidence: 99%

Water drinking test in glaucoma management: a review of the literature

Khoo¹,

Cheng²,

Din³

2022

MyJO

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“…This is somewhat different from results with glaucomatous eyes. Tran et al reported mean peak IOP was highest at 45 min after water ingestion, whereas Hatanaka et al found that, on average, mean peak IOP was highest at 30 min, in a cohort of 88 eyes with ocular hypertension or primary open‐angle glaucoma (POAG).…”

Section: Interpreting Resultsmentioning

confidence: 99%

Applications of the water drinking test in glaucoma management

Susanna

Clement

Goldberg

et al. 2017

Clinical Exper Ophthalmology

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Intraocular pressure (IOP) peaks and means have been considered important factors for glaucoma onset and progression. However, peak IOP detection depends only on appropriated IOP checks at office visits, whereas the mean IOP requires longitudinal IOP data collection and may be affected by the interval between visits. Also, IOP peak assessment is necessary to verify if the peak pressure of a given patient is in target range, to evaluate glaucoma suspect risk, the efficacy of hypotensive drugs and to detect early loss of IOP control. The water-drinking test has gained significant attention in recent years as an important tool to evaluate IOP peaks and instability. The main objective of this review was to present new findings and to discuss the applicability of the water-drinking test in glaucoma management.

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“…43 First, IOP peak results obtained through the WDT tend to systematically overestimate those observed during other IOP variation tests, such as diurnal tension curves, postural change test, and caffeine test. 28,44,45 This suggests that the water overload promoted during the WDT could lead to a non-physiological IOP rise. Second, WDT results can be influenced by factors not related to glaucoma, such as patient body mass index and use of systemic antihypertensive drugs.…”

Section: Discussionmentioning

confidence: 99%

Comparison between provocative test-based and long-term intraocular pressure parameters in patients with stable open-angle glaucoma

Almeida

Scoralick

Dias

et al. 2020

European Journal of Ophthalmology

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Purpose: To compare provocative test-based and long-term intraocular pressure variation parameters in patients with stable open-angle glaucoma. Methods: A prospective observational study was carried out in which stable open-angle glaucoma patients (⩾3 years of follow-up without any changes on current medical regimen) were consecutively enrolled. All patients were submitted to a water-drinking test. Long-term intraocular pressure parameters were obtained from isolated intraocular pressure measurements from each visit (⩾5 visits). We investigated the correlation and agreement between the following water-drinking test and long-term intraocular pressure parameters: mean, peak, and fluctuation. In addition, the percentage of eyes with significant intraocular pressure peaks during the water-drinking test (defined as a difference ⩾25% between water-drinking test intraocular pressure peak and mean long-term intraocular pressure) was assessed. Results: Sixty-three eyes from 63 open-angle glaucoma patients (mean age, 60.7 ± 11.8 years) were included. Mean and water-drinking test intraocular pressure peak correlated significantly with mean ( r = 0.67) and maximum long-term intraocular pressure ( r = 0.52), respectively ( p < 0.01). The correlation between water-drinking test intraocular pressure fluctuation and long-term intraocular pressure fluctuation was not significant ( p = 0.45). Limits of agreement from Bland–Altman plots exceeded the maximum allowed difference between methods (3 mm Hg) for all the intraocular pressure parameters analyzed, suggesting poor agreement between water-drinking test–derived and long-term intraocular pressure values. Overall, significant water-drinking test intraocular pressure peaks were observed in 39.7% of these eyes with stable open-angle glaucoma. Conclusion: Although some water-drinking test–based and long-term intraocular pressure parameters correlate significantly, water-drinking test results may not reflect the long-term intraocular pressure profile of stable open-angle glaucoma patients, as their agreement is poor. Many of these patients may experience significant water-drinking test intraocular pressure peaks, despite long-standing stable disease and unchanged medical regimen.

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Rise of intraocular pressure in a caffeine test versus the water drinking test in patients with glaucoma

Abstract: The rise in intraocular pressure was greater with water drinking test than the caffeine test. Caffeine does not appear to provide an alternative for patients unable to tolerate the water drinking test.

Cited by 16 publications

References 34 publications

Water drinking test in glaucoma management: a review of the literature

Water drinking test in glaucoma management: a review of the literature

Applications of the water drinking test in glaucoma management

Comparison between provocative test-based and long-term intraocular pressure parameters in patients with stable open-angle glaucoma

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