Ring-Shaped Morphology of “Crew-Cut” Aggregates from ABA Amphiphilic Triblock Copolymer in a Dilute Solution

Zhu, Jintao; Liao, Yonggui; Jiang, Wei

doi:10.1021/la0361565

Cited by 109 publications

(130 citation statements)

References 45 publications

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“…Toroids have also been reported for various systems, and in each case the driving force for structure formation appears to be minimization of the end cap energy. [24][25][26][27] Spherical vesicles are not the only possible bilayer-type structures generated through self-assembly. Bilayer tubules have been generated from direct dissolution of copolymers in solvent mixtures followed by dialysis [28,29] ( Figure 2c) and also in pure organic solvents, [30] with tubes up to centimetres in length being obtained.…”

Section: Introductionmentioning

confidence: 99%

Self‐Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications

Blanazs

Armes

Ryan

2009

Macromol. Rapid Commun.

1,392

1,370

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The ability of amphiphilic block copolymers to self‐assemble in selective solvents has been widely studied in academia and utilized for various commercial products. The self‐assembled polymer vesicle is at the forefront of this nanotechnological revolution with seemingly endless possible uses, ranging from biomedical to nanometer‐scale enzymatic reactors. This review is focused on the inherent advantages in using polymer vesicles over their small molecule lipid counterparts and the potential applications in biology for both drug delivery and synthetic cellular reactors.magnified image

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Section: Introductionmentioning

confidence: 99%

Self‐Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications

Blanazs

Armes

Ryan

2009

Macromol. Rapid Commun.

1,392

1,370

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“…Hence, the formation of toroidal micelle information has been restricted for a few specific systems (Huang et al, 2009). Toroidal micelles have been observed to form from ABC, ABA and AB amphiphilic block copolymer (Fu et al, 2009;Hoogenboom et al, 2008;Liu et al, 2008;Tsitsilianis et al, 2008;Reynhout et al, 2007;LaRue et al, 2006;Zhu et al, 2004). Toroids shape formed through the elimination of high free energy end caps of cylindrical micelles and also by the perforation of disc-like micelles which were energetically unfavorable spherical micelle (Cui et al, 2009).…”

Section: Resultsmentioning

confidence: 99%

Computational simulation of palm kernel oil-based esters nano-emulsions aggregation as a potential parenteral drug delivery system

Faujan

Karjiban

Kashaban

et al. 2019

Arabian Journal of Chemistry

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The self-assembled structure of palm kernel oil-based esters (PKOEs) nano-emulsions has shown a great potential used for parenteral drug delivery applications. Here, all-atom level molecular dynamics (MD) was applied to investigate the aggregation process of PKOEs nano-emulsion system. The system consisted of palm kernel oil-based esters (PKOEs) and dipalmitoylphosphatidylcholine (DPPC) in water. The ratio of all constituents was taken from the homogenous region of a ternary phase diagram determined experimentally. The molecules started to aggregate very rapidly from random configurations. A doughnut-like toroidal assembled structure formed at 50 ns with PKOEs surrounded by DPPC molecules. The structural and dynamical properties of the self-assembled doughnut-like toroidal aggregate were analyzed using the principle moment of inertia, eccentricity and radius of gyration. The aggregation structures were compact with the average radius of gyration of 4.10 (±0.02) nm over the last 5 ns. Additionally, both hydrophobic

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“…Recently, toroidal core-shell structures have been prepared by the self-assembly of various block copolymers, [14][15][16][17] the triblock copolymer poly(4-vinyl pyridine)-block-polystyrene block-poly(4-vinyl pyridine) (PVP-block-PS-block-PVP) is representative among them. The walls of the assembled rings contain a hydrophobic PS inner core and a hydrophilic exterior corona composed of the PVP block (indicated by Scheme 1), which is verified by a favorable complexation with Zn 2þ , which leads to the formation of ZnS within the shell.…”

Section: Communicationmentioning

confidence: 99%

Templated Synthesis of Composite Rings Using Core‐Shell Toroids

Wei

et al. 2007

Macromol. Rapid Commun.

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In difference to compact objects of a similar size, toroidal structures have some distinguishing properties that originate from their open inner cavity and closed circuit. Here, a general facile methodology is developed to prepare composite rings with varied compositions on a large scale by using core‐shell toroids assembled from tri‐block copolymers of poly(4‐vinyl pyridine) (PVP)/polystyrene (PS)/PVP. Taking advantage of the complexation ability of the PVP shell, varied components that range from polymers, inorganic materials, metals and their compounds, as well as pre‐formed nanoparticles are introduced to the toroidal structures to form composite nanostructures. Metal ions can be adsorbed by PVP through complexation. After in situ reduction, a large number of metal‐based functional materials can be prepared. PVP is alkaline, and thus capable of catalyzing the sol‐gel process to generate an inorganic shell. Furthermore, pre‐formed nanoparticles can also be absorbed by the shell through specific interactions. The PS core is not infiltrative during synthesis, and hollow rings can be derived after the polymer templates are removed.magnified image

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Ring-Shaped Morphology of “Crew-Cut” Aggregates from ABA Amphiphilic Triblock Copolymer in a Dilute Solution

Cited by 109 publications

References 45 publications

Self‐Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications

Self‐Assembled Block Copolymer Aggregates: From Micelles to Vesicles and their Biological Applications

Computational simulation of palm kernel oil-based esters nano-emulsions aggregation as a potential parenteral drug delivery system

Templated Synthesis of Composite Rings Using Core‐Shell Toroids

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