Ring-Opening Sulfonylation of Cyclic Sulfonium Salts with Sodium Sulfinates under Transition-Metal- and Additive-Free Conditions
Li-Hua Yang,
Xin-Si Liu,
Chu Liu
et al.
Abstract:Incorporating a sulfonyl group into parent molecules
has been shown
to effectively improve their synthetic applications and bioactivities.
In this study, we present a straightforward and practical approach
for the ring-opening reaction of alkenyl–aryl sulfonium salts
with sodium sulfinates to produce a range of sulfur-containing alkyl
sulfones. This method offers the benefits of mild reaction conditions,
easily accessible raw materials, wide substrate applicability, good
functional group compatibility, and ope… Show more
A convenient and practical method for the synthesis of various S-alkyl dithiocarbamates through three-component reaction of sulfonium salts, CS 2 and amines has been developed. The reaction proceeds efficiently without any catalyst and additive under mild and open-air conditions, making it potential applications in pharmaceutical chemistry and sulfur chemistry.
A convenient and practical method for the synthesis of various S-alkyl dithiocarbamates through three-component reaction of sulfonium salts, CS 2 and amines has been developed. The reaction proceeds efficiently without any catalyst and additive under mild and open-air conditions, making it potential applications in pharmaceutical chemistry and sulfur chemistry.
A simple and practical method for the synthesis of S-alkyl phosphorothioates/phosphorodithioates through the three-component reaction of cyclic sulfonium salts with S8, H-phosphonates, or P4S10, and alcohols was readily developed.
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