“…The Dimroth isomer trifluoro-N-imidazo[1,2a]pyridine-3-ylacetamide was also detected by HPLC, T r = 1.25 min (22%). Analysis of 11: 1 H NMR (CDCl 3 , 300 MHz) δ 5.56 (br s, 1H), 6.90 (dd, 1H, J = 6.9, 7.8 Hz), 7.28 (dd, 1H, J = 9.1, 7.8 Hz), 7.49 (d, 1H, J = 9.1 Hz), 8.16 (d, 1H, J = 6.8 Hz), 8.18 (s, 1H); 13 C NMR (CDCl 3 , 75 MHz) δ 102.9, 113.3, 114.5 (q), 116.4, 126.0, 126.2, 139.3, 142.0, 154.9 (q); 19 Synthesis of 12a−e. To a suspension of 1 g of compound 11 (4.36 mmol) in 9 mL of aqueous 5 N sodium hydroxide solution was added 1 mL of THF.…”