Rightward bias in right hemisphere infarct patients with or without thrombolytic treatment and in healthy controls

Kettunen, Jani E; Laihosalo, Mari; Ollikainen, Jyrki; Dastidar, Prasun; Nurmi, Laura; Koivisto, Anna‐Maija; Jehkonen, Mervi

doi:10.1080/13554794.2011.608367

Cited by 3 publications

(1 citation statement)

References 23 publications

(15 reference statements)

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“…In a study of patients with right hemisphere stroke, Laihosalo et al (2011) found that patients treated with t-PA demonstrated significantly better visuoconstructional abilities compared to non-treated patients 4 days post-stroke. Treated patients also demonstrated an overall reduction in the presence of visual neglect and improved attentional processing (Kettunen et al 2012a(Kettunen et al , 2012b. Similarly, Jacquin et al (2014) found that the severity of aphasia was significantly milder in left hemisphere stroke patients treated with t-PA 1 week post-stroke; however, these differences did not persist when measured at 3 months.…”

Section: Discussionmentioning

confidence: 92%

What does cognitive screening reveal about early cognitive performance following endovascular clot retrieval and intravenous thrombolysis in acute ischaemic stroke?

Humphrey,

Pike,

Long

et al. 2024

Brain I.

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Background Little is known regarding cognitive outcomes following treatment with endovascular clot retrieval (ECR) and intravenous tissue plasminogen activator (t-PA). We aimed to determine if there were any differences on a measure of cognitive screening between patients treated with ECR, t-PA, and those who were managed conservatively. Methods The medical records of ischaemic stroke patients admitted to Monash Medical Centre between January 2019 and December 2019 were retrospectively reviewed. Information extracted from medical records included age, sex, National Institutes of Health Stroke Scale at presentation, location of occlusion, treatment type, medical history, and cognitive screening performance measured by the Montreal Cognitive Assessment (MoCA). Results Eighty-two patients met the inclusion criteria (mean age = 66.5 ± 13.9; 49 male, 33 female). Patients treated with ECR performed significantly better on the MoCA (n = 36, 24.1 ± 4.3) compared to those who were managed conservatively (n = 26, 20.7 ± 5.5). Performance for patients treated with t-PA (n = 20, 23.9 ± 3.5) fell between the ECR and conservative management groups, but they did not significantly differ from either. Conclusion Our retrospective chart review found that ischaemic stroke patients treated with ECR appear to perform better on cognitive screening compared to patients who are managed conservatively. We also found that patients treated with ECR and t-PA appear to have similar cognitive screening performances in the acute stages following ischaemic stroke, although this finding is likely to have been impacted by group differences in stroke characteristics and may reflect the possibility that the ECR group performed better than expected based on their stroke severity.

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