Right ventricular function in patients after acute myocardial infarction assessed with phase contrast MR velocity mapping encoded in three directions

Phase-contrast magnetic resonance (MR) imaging is a well-known but undervalued method of obtaining quantitative information on blood flow. Applications of this technique in cardiovascular MR imaging are expanding. According to the sequences available, phase-contrast measurement can be performed in a breath hold or during normal respiration. Prospective as well as retrospective gating techniques can be used. Common errors in phase-contrast imaging include mismatched encoding velocity, deviation of the imaging plane, inadequate temporal resolution, inadequate spatial resolution, accelerated flow and spatial misregistration, and phase offset errors. Flow measurements are most precise if the imaging plane is perpendicular to the vessel of interest and flow encoding is set to through-plane flow. The sequence should be repeated at least once, with a high encoding velocity used initially. If peak velocity has to be estimated, flow measurement is repeated with an adapted encoding velocity. The overall error of a phase-contrast flow measurement comprises errors during prescription as well as errors that occur during image analysis of the flow data. With phase-contrast imaging, the overall error in flow measurement can be reduced to less than 10%, an acceptable level of error for routine clinical use.

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“…There have been promising studies on use of phase-contrast imaging for analysis of myocardial wall motion (52,53).…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular Flow Measurement with Phase-Contrast MR Imaging: Basic Facts and Implementation

Lotz

Meier²,

Leppert³

et al. 2002

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572

465

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“…A smaller difference in the right ventricular ejection fraction values would probably have been observed if we had used the first-pass radionuclide technique [32] as reference method. Other imaging methods such as MR [11,12,33,34] have recently been tested to evaluate the right and left cardiac function with promising results. However this technique was not used in the present study due to the limited equipment availability and clinical situation.…”

Section: Feasibilitymentioning

confidence: 99%

Evaluation of biventricular ejection fraction with ECG-gated 16-slice CT: preliminary findings in acute pulmonary embolism in comparison with radionuclide ventriculography

et al. 2005

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This study aimed to assess the feasibility of cardiac global function evaluation during a whole-chest multi-slice CT (MSCT) acquisition in patients referred for suspicion of pulmonary embolism (PE), and to compare the results with planar equilibrium radionuclide ventriculography (ERNA). Ten consecutive haemodynamically stable patients (six female, four male; mean age 69.7 years; heart rate 65-99 bpm) with suspicion of PE underwent an MSCT and ERNA within a 6 h period. CT acquisition was performed after contrast medium injection by using 16x1.5 mm collimation and retrospective ECG gating. Left ventricular (LVEF) and right ventricular (RVEF) ejection fractions were calculated using dedicated three-dimensional software. Relationships between measurements obtained with MSCT and ERNA were assessed using linear regression analysis and reliability of MSCT was assessed with intra-class correlation coefficient. Bland-Altman analysis was performed to calculate limits of agreement between MSCT and ERNA. MSCT was performed successfully in ten patients with a mean acquisition time of 16.5+/-2.8 s. Functional cardiac evaluation was possible on CT for all patients except for one due to poor opacification of right ventricle. Linear regression analysis showed a good correlation between MSCT and ERNA for the LVEF (R=0.91) and the RVEF (R=0.89) measurements. Intra-class correlation was superior for LVEF (0.92) than for the RVEF (0.68). Bland-Altman plots demonstrated that MSCT substantially overestimated the ERNA RVEF. Morphological CT data demonstrated PE in four of ten of patients and alternative diagnoses in five of ten patients. Our study reveals that MSCT with retrospective ECG gating may provide in one modality a morphological and a functional cardiopulmonary evaluation. Comparison with ERNA demonstrated a good correlation for both ventricular ejection fractions.

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“…Finally, myocardial motion velocity may be evaluated by PC-CMR. This approach can acquire images in multiple oblique planes, allowing the operator to choose in-plane or through-plane velocity acquisitions [55] with a high spatial and temporal resolution [65]. …”

Section: Introductionmentioning

confidence: 99%

The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance

Noureldin

Liu

Nacif

et al. 2012

Journal of Cardiovascular Magnetic Resonance

150

132

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Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the heart. HCM is characterized by a wide range of clinical expression, ranging from asymptomatic mutation carriers to sudden cardiac death as the first manifestation of the disease. Over 1000 mutations have been identified, classically in genes encoding sarcomeric proteins. Noninvasive imaging is central to the diagnosis of HCM and cardiovascular magnetic resonance (CMR) is increasingly used to characterize morphologic, functional and tissue abnormalities associated with HCM. The purpose of this review is to provide an overview of the clinical, pathological and imaging features relevant to understanding the diagnosis of HCM. The early and overt phenotypic expression of disease that may be identified by CMR is reviewed. Diastolic dysfunction may be an early marker of the disease, present in mutation carriers prior to the development of left ventricular hypertrophy (LVH). Late gadolinium enhancement by CMR is present in approximately 60% of HCM patients with LVH and may provide novel information regarding risk stratification in HCM. It is likely that integrating genetic advances with enhanced phenotypic characterization of HCM with novel CMR techniques will importantly improve our understanding of this complex disease.

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Right ventricular function in patients after acute myocardial infarction assessed with phase contrast MR velocity mapping encoded in three directions

Cited by 21 publications

References 19 publications

Cardiovascular Flow Measurement with Phase-Contrast MR Imaging: Basic Facts and Implementation

Cardiovascular Flow Measurement with Phase-Contrast MR Imaging: Basic Facts and Implementation

Evaluation of biventricular ejection fraction with ECG-gated 16-slice CT: preliminary findings in acute pulmonary embolism in comparison with radionuclide ventriculography

The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance

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