Right Ventricular Compression Mimicking Brugada-Like Electrocardiogram in a Patient with Recurrent Pectus Excavatum

Ahn, Jinhyun; Choi, Jong Il; Shim, Jaemin; Lee, Sung Ho; Kim, Young Hoon

doi:10.1155/2017/3047937

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…A narrow thorax may explain several cardiac issues. Several case reports have reported the existence of Brugada ECG patterns in patients with a narrow thoracic deformity, including pectus excavatum 9,14,15 , anterior mediastinal masses 16 , and the surgical treatment of esophageal cancer followed by retro-sternum placement of the stomach 17 .…”

Section: Relationship Between Thoracic Size and Brsmentioning

confidence: 99%

Narrow Anteroposterior Thorax may be Associated with Brugada Syndrome due to Chronic Mechanical Compression of the Right Ventricular Outflow Tract

Ishii

Nakagawa

Abe

et al. 2020

Preprint

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Introduction: Recent research has shown that Brugada syndrome (BrS) is associated with interstitial fibrosis in the right ventricular outflow tract (RVOT) epicardium, thus suggesting that BrS does not just involve cardiac channelopathy but also includes cardiomyopathy. On the other hand, Brugada pattern ECGs are often observed in patients with pectus excavatum. The purpose of this study was to investigate whether thoracic deformity, along with mechanical compression of RVOT, were associated with BrS. Methods and Results: We recruited 17 male patients with symptomatic BrS, 32 male patients with asymptomatic BrS, and 30 age-matched male controls. Using computed tomography (CT) scans, we measured the maximal internal transverse diameter of the thorax (T) and the shortest anteroposterior depth from the internal aspect of the sternum to the anterior cortex of the vertebral body (D) at the level of the RVOT. We then evaluated the fragmented QRS (f-QRS) in the right precordial leads. D was significantly shorter, while T divided by D (T/D) was significantly greater, in patients with symptomatic and asymptomatic BrS than in the controls. Six patients with pectus excavatum (T/D[?]3.25) were included in the BrS population. The f-QRSs was more frequently observed in symptomatic and asymptomatic BrS patients than in controls. The positive spikes within the QRS complex were more prevalent in patients with a greater T/D. Conclusion: Our results suggested that a narrow anteroposterior thoracic space could be associated with BrS via mechanical compression of the RVOT.

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Section: Relationship Between Thoracic Size and Brsmentioning

confidence: 99%

Narrow Anteroposterior Thorax may be Associated with Brugada Syndrome due to Chronic Mechanical Compression of the Right Ventricular Outflow Tract

Ishii

Nakagawa

Abe

et al. 2020

Preprint

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2018 KHRS Guidelines for Catheter Ablation of Ventricular Arrhythmias – Part2

Kim¹,

Kim²,

Kim³

et al. 2018

Int J Arrhythm

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The recommendations outlined constitute the first clinical practice guidelines of the Korean Heart Rhythm Society regarding catheter ablation of ventricular arrhythmias (VA). This is a guideline PART 2, which includes VA in the structurally normal heart, inherited primary arrhythmia syndromes, VA related to congenital heart disease, as well as VA and sudden cardiac death observed in specific populations. In the structurally normal heart, treatment is guided by the occurrence of symptoms or the frequency of arrhythmias that cause ventricular dysfunction over time. Catheter ablation can be recommended in patients in whom anti-arrhythmic medications are ineffective. The sites of origin of arrhythmic activity are known to be the outflow tract, fascicles, papillary muscle, or the annulus. Specific cardiac channelopathies include congenital long QT and Brugada syndrome. This guideline discusses the diagnostic criteria, risk stratification, and treatment of these syndromes. We have included recommendations for adult congenital heart disease. Moreover, we have discussed the management of VA occurring in specific populations such as in patients with psychiatric and neurological disorders, pregnant patients, those with obstructive sleep apnea or drug-related pro-arrhythmias, athletes, and elderly patients.

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Inherited arrhythmia syndrome predisposing to sudden cardiac death

Choi

2021

Korean J Intern Med

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Inherited arrhythmia (IA) is one of the main causes of sudden cardiac death (SCD) in young people, and is reported to be more prevalent as a cause of SCD in Asia compared to western countries. IA is a group of genetic disorders caused by mutations in gene encoding cardiac ion channels, leading to electrophysiological characteristics that often occur in the absence of structural abnormalities. Channelopathies, such as long QT syndrome (LQTS) and Brugada syndrome (BrS), have a potential risk of life threatening ventricular tachyarrhythmias that predispose into SCD, although early prediction and prevention for the risk remains challenging. Recent advances in genetic testing enable physicians to facilitate risk stratification as well as precise diagnosis for IA despite of ongoing debates for the implications. Herein, we will provide an epidemiological data, a pathophysiological overview, and the current clinical approach focusing on IAs related to SCD. In addition, we will review the general issues arising from genetic testing for IAs.

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Right Ventricular Compression Mimicking Brugada-Like Electrocardiogram in a Patient with Recurrent Pectus Excavatum

Cited by 3 publications

References 9 publications

Narrow Anteroposterior Thorax may be Associated with Brugada Syndrome due to Chronic Mechanical Compression of the Right Ventricular Outflow Tract

Narrow Anteroposterior Thorax may be Associated with Brugada Syndrome due to Chronic Mechanical Compression of the Right Ventricular Outflow Tract

2018 KHRS Guidelines for Catheter Ablation of Ventricular Arrhythmias – Part2

Inherited arrhythmia syndrome predisposing to sudden cardiac death

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