Right-Sided Infective Endocarditis Secondary to Intravenous Drug Abuse

Meel, Ruchika

doi:10.5772/intechopen.84319

Cited by 8 publications

(10 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Vegetation size correlates with mortality. TVE vegetations are highly mobile, which explains the higher rate of pulmonary embolic phenomenon associated with the entity [ 5 – 7 , 10 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Surgical treatment is needed in 5-16% of TVE, and it has to be considered in the following situations: (1) intractable right-sided heart failure with poor response to diuretics, (2) persistent bacteremia despite the use of appropriate antimicrobial therapy, (3) large vegetation (>20 mm) that does not diminish in size despite repeated embolism, (4) fungal endocarditis, (5) concomitant left-sided IE, and (7) prostatic valve endocarditis. Valvectomy, valve replacement, or repair are the common surgeries performed for tricuspid valve endocarditis [ 7 , 10 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Isolated Native Tricuspid Valve Endocarditis in a Nonintravenous Drug User

Shibru

Greffie

Abay

et al. 2020

Case Reports in Cardiology

View full text Add to dashboard Cite

Infective endocarditis (IE) is a disease characterized by high morbidity and mortality. IE was first described in the mid-16th century. Right-sided infective endocarditis (RSIE) represents 5% to 10% of all IE episodes in adults. RSIE can be divided into three groups according to the underlying risk factors: intravenous drug users (IDUs), cardiac device carriers, and the “three noes” group (no left-sided IE, no IDUs, and no cardiac devices). Tricuspid valve endocarditis in nonintravenous drug users can occur in a variety of conditions including congenital heart disease, intracardiac devices, central venous catheters, and immunologically debilitated patients. Due to the rareness of isolated native nonrheumatic tricuspid valve endocarditis, here, we like to present an 18-year-old male from rural Ethiopia with the diagnosis of isolated native tricuspid valve endocarditis that was treated and cured.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Isolated Native Tricuspid Valve Endocarditis in a Nonintravenous Drug User

Shibru

Greffie

Abay

et al. 2020

Case Reports in Cardiology

View full text Add to dashboard Cite

show abstract

“…Известно, что риск развития инфекционного эндокардита среди потребителей инъекционных наркотиков (ПИН) выше, чем у пациентов с ревматическими пороками сердца и протезированными клапанами. Формирование подобной ситуации обусловлено как свойствами вводимых наркотических препаратов, которые могут вызывать непосредственное повреждение клапанов сердца, способствовать образованию тромбов и легочной гипертензии, так и заносом микробной флоры в системный кровоток при использовании нестерильных игл [2,3,4]. По данным литературы, частота заболеваемости инфекционным эндокардитом среди таких пациентов составляет от 2 до 5%, что в 1000 раз больше заболеваемости этой нозологией в общей популяции [4,5].…”

Section: Introductionunclassified

“…Формирование подобной ситуации обусловлено как свойствами вводимых наркотических препаратов, которые могут вызывать непосредственное повреждение клапанов сердца, способствовать образованию тромбов и легочной гипертензии, так и заносом микробной флоры в системный кровоток при использовании нестерильных игл [2,3,4]. По данным литературы, частота заболеваемости инфекционным эндокардитом среди таких пациентов составляет от 2 до 5%, что в 1000 раз больше заболеваемости этой нозологией в общей популяции [4,5]. Сочетание ВИЧинфекции и инфекционного эндокардита -это сложная медицинская проблема.…”

Section: Introductionunclassified

“…Наличие иммунодефицитного состояния оказывает негативное влияние на течение бактериальной инфекции. В свою очередь, выраженные метаболические нарушения, развивающиеся при бактериемии и сопутствующей ей токсинемии, дополнительно угнетают иммунную систему [4].…”

Section: Introductionunclassified

See 1 more Smart Citation

Infectious endocarditis in HIV-infected intensive care unit patients

Kharlamova

Voznesenskiy

Ermak

et al. 2022

jour

View full text Add to dashboard Cite

Infective endocarditis (IE) is one of the most common cardiac complications in HIV patients who are intravenous drug addicts. The presence of IE and secondary diseases in immunocompromised individuals usually requires specific diagnostic and therapeutic approach.Aim: Optimizing the diagnosis of IE in patients with advanced HIV/AIDS.Materials and methods We reviewed 429 case records of HIV/AIDS ICU patients using the modified duke criteria for diagnosis of infective endocarditis. Statistical significance (p <0.05) of data was assessed using the χ2 test.Results. 25 patients were diagnosed with IE. The male gender dominated – 68%. Mean age was 38. 60% had stage 4B HIV infection. 68% were ART naive. The medium viral load was 294560 copies / ml, while the medium CD4 count was 218 cells / μl. Fever of >38°C was a key symptom found in all patients. Blood cultures were positive in 60% cases. 80% had a high C reactive protein (CRP), and 44% had CRP levels above 100 mg/l. Procalcitonin (PCT) levels were increased in 52%. Echocardiogram revealed IE in 92%. Pneumonia was diagnosed in 92%. Fatal outcome occurred in 76%. Anemia was a predictor of severe outcome (p<0.002), while patients with leukocytosis had good prognosis (p<0.05).Conclusion. Infective endocarditis is a common complication among HIV IDUs. The most common diagnostic criteria are fever >38°C, pneumonia, anemia, leukocytosis, thrombocytopenia and echocardiographic findings. The levels of the hemoglobin and WBCs could evaluate prognosis of the disease outcome.

show abstract