Right Native Lung Pneumonectomy Due to over Inflation Three Years after Left Single Lung Transplantation for Pulmonary Lymphangioleiomyomatosis

Liu, Fabing; Ruan, Zheng; Wang, Shaohua; Lin, Qiang

doi:10.5761/atcs.cr.13-00133

Cited by 7 publications

(3 citation statements)

References 5 publications

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“…12 To remove the compression of transplanted organ, lung volume reduction surgery is performed, native lung pneumonectomy is not frequently reported. 13 In analysis performed by King et al out of 180 patients who underwent SLuTx, 25 developed complications in the native lung. In this group, 11 patients required native lung pneumonectomy.…”

Section: Discussionmentioning

confidence: 99%

Native lung hyperinflation after single lung transplantation – case report and literature review

et al. 2021

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Introduction: Single lung transplantation (SLuTx) is a challenging operation for patients with end-stage chronic pulmonary diseases. After surgery, native lung hyperinflation (NLH) and a mediastinal shift may develop, which changes the anatomical position of the lungs and heart and may lead to graft compression. Aim: We present a case report of a patient who developed NLH after SLuTx. We discuss the treatment methods and compare the outcomes with other case reports and analysis from world literature. Case study: A 56-year-old female patient was diagnosed with end-stage chronic obstructive pulmonary disease (FEV1 < 30%) and qualified for right SLuTx. After the procedure, spirometry revealed gradual loss in FEV1. Radiological images confirmed NLH and compression of the graft. Therefore, a native lung pneumonectomy was performed with positive outcomes. Results and discussion: NLH is a known complication of SLuTx. Typically, lung volume reduction surgery is performed to reduce the compression and a pneumonectomy is a rare treatment, even in centres with extensive experience with SLuTx. Conclusions: Despite SLuTx being a common approach in many pulmonary diseases, NLH should be always taken into consideration. Hyperinflation could cause a dangerous loss of respiratory efficiency and require invasive surgeries for lung transplant recipients.

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Section: Discussionmentioning

confidence: 99%

Native lung hyperinflation after single lung transplantation – case report and literature review

et al. 2021

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“…Contralateral pneumonectomy after SLT has been reported in only 3 patients (ages 46, 56, and 66 years ( Table 3 ) [ 9 – 11 ]. Intractable air leak was incriminated in 1 case (17 days after SLT) [ 11 ] and progressive hyperinflation of the native lung in the other 2 patients (3 years and 12 years after SLT) [ 9 , 10 ]. In our patient, clinical improvement was achieved transiently after lung volume reduction and she underwent completion pneumonectomy 27 years after right SLT.…”

Section: Discussionmentioning

confidence: 99%

Contralateral Pneumonectomy 27 Years After Right Single-Lung Transplantation for Emphysema: A Case Report

et al. 2022

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“…Due to the different compliance between the native and the transplanted lungs, the native lung overinflation can be a serious complication after SLT for LAM, that is likely to occur after SLT for COPD. Liu et al reported a case of pneumonectomy of an overinflated native lung after SLT for LAM that resulted in improved lung function [9].…”

Section: Introductionmentioning

confidence: 99%

Correlation between the native lung volume change and postoperative pulmonary function after single lung transplantation for lymphangioleiomyomatosis: Evaluation of lung volume by three-dimensional computed tomography volumetry

et al. 2019

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PurposeWhereas native lung overinflation has been thought to happen in recipients of single lung transplantation for lymphangioleiomyomatosis because of its increased compliance, there is no study that has reported the details on the change of the native lung volume after single lung transplantation by three-dimensional computed tomography volumetry. The purpose of the present study was to evaluate the lung volume after single lung transplantation for lymphangioleiomyomatosis by three-dimensional computed tomography volumetry and investigate the correlation between the native lung volume change and postoperative pulmonary function.MethodsWe retrospectively reviewed the data of 17 patients who underwent single lung transplantation for lymphangioleiomyomatosis. We defined the ratio of the native lung volume to total lung volume (N/T ratio) as an indicator of overinflation of the native lung. In order to assess changes in the N/T ratio over time, we calculated the rate of change in the N/T ratio which is standardized by the N/T ratio at 1 year after single lung transplantation: rate of change in N/T ratio (%) = {(N/T ratio at a certain year)/(N/T ratio at 1 year)– 1}× 100.ResultsWe investigated the correlations between the N/T ratio and the pulmonary function test parameters at 1 year and 5 years; however, there was no significant correlation between them. On the other hand, there was a significant negative correlation between the rate of change in the N/T ratio and that in forced expiratory volume in 1 second %predicted (%FEV1) at 5 years after single lung transplantation.ConclusionThe single lung transplantation recipients for lymphangioleiomyomatosis showed increased rate of change in the N/T ratio in the long-time course after lung transplantation with the decrease of %FEV1. We expect that these cases will probably cause the overinflation of the native lung in the future.

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Right Native Lung Pneumonectomy Due to over Inflation Three Years after Left Single Lung Transplantation for Pulmonary Lymphangioleiomyomatosis

Cited by 7 publications

References 5 publications

Native lung hyperinflation after single lung transplantation – case report and literature review

Native lung hyperinflation after single lung transplantation – case report and literature review

Contralateral Pneumonectomy 27 Years After Right Single-Lung Transplantation for Emphysema: A Case Report

Correlation between the native lung volume change and postoperative pulmonary function after single lung transplantation for lymphangioleiomyomatosis: Evaluation of lung volume by three-dimensional computed tomography volumetry

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