Right Hepatic Lobe Donation: Impact on Donor Quality of Life

Sevmiş, Ş.; Diken, T.; Boyvat, Fatih; Torgay, Adnan; Haberal, Mehmet

doi:10.1016/j.transproceed.2007.02.045

Cited by 23 publications

(32 citation statements)

References 13 publications

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“…[28,29] In our study, 60% of donors returned to work within 3 months after surgery. However, physical function had yet to return to the preoperative state by 3 months in 40% of donors, which prevented them from returning to work.…”

Section: Discussionmentioning

confidence: 90%

Mental health status after living donor hepatectomy

et al. 2017

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Donor safety and preservation of donor health after living liver donation are of paramount importance. In addition, the preoperative mental state of a donor is an important factor in determining the psychological impact of donor hepatectomy. Thus, we aimed to explore the mental health status of living liver donors after hepatectomy. We enrolled 60 donors who were scheduled to undergo living donor hepatectomy during the period January 2014 to March 2015 at a single medical center. Mental health status was measured before and 3 months after surgery using 3 self-report questionnaires, namely the Center for Epidemiologic Studies Depression Scale (CES-D) to assess depressive symptoms, the World Health Organization Quality of Life (WHOQOL-BREF) questionnaire to measure quality of life, and the Chinese Health Questionnaire (CHQ) to screen for minor psychiatric disorders. A comparison of the pre- and postdonation CES-D scores revealed a significant reduction in depressive symptoms after surgery (P = .031). There were significant improvements in the physical health domain (P = .031), the psychological health domain (P = .005), the social relationships domain (P = .005), and the environmental health domain (P = .010) of the WHOQOL-BREF. There were no significant changes in CHQ scores after donor hepatectomy (P = .136). All donors reported that they would donate again if required. Approximately one-third (33.3%) of donors experienced more pain than they had anticipated in the immediate postoperative period, and 20.0% of donors had complications after donor hepatectomy. Donor mental health status tended to improve as donors regained physical function during the 1st 3 months of recovery. Long-term monitoring of living donors’ mental health is needed to minimize the adverse psychological outcomes of living liver donation.

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Section: Discussionmentioning

confidence: 90%

Mental health status after living donor hepatectomy

et al. 2017

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“…Despite developments in surgical techniques and experiences, a complication rate of approximately 38% and a mortality rate of 0.2% has been reported. Fortunately, almost all donors return to their normal lives at 3-6 months postoperatively (6)(7)(8). There is a higher rate of complications and mortality in right lobe donors with a long-term negative effect on quality of life.…”

Section: Discussionmentioning

confidence: 99%

“…There is a higher rate of complications and mortality in right lobe donors with a long-term negative effect on quality of life. The only reason of the higher mortality and morbidity rate in right lobe donors is the greater liver volume to be removed (8,9). In the current study, 39 donors underwent right hepatectomy while 7 underwent left lobe or left lateral segment resection.…”

Section: Discussionmentioning

confidence: 99%

“…The donor is mobilized after 6 hours. The urinary catheter is removed on the 1 st postoperative day and the central venous catheter on the 3 rd day on condition that the platelet count is 80000/mm 3 [8][9][10][11][12][13][14][15][16][17][18][19][20] in the group with coagulopathy, and 27,12±4,11 (34,(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) in the group without coagulopathy. The demographic data were similar in both groups.…”

Section: Postoperative Follow-upmentioning

confidence: 99%

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Analysis of risk factors affecting coagulopathy after donor hepatectomy in a newly established liver transplant center

et al. 2017

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Objective: As might be expected, living donor liver surgery is associated with serious morbidity and mortality risks. Coagulopathy after donor hepatectomy is an important risk factor affecting morbidity. In this study, risk factors affecting the development of coagulopathy after donor hepatectomy was evaluated in a newly-established liver transplant center. Material and Methods:A retrospective evaluation of 46 liver donors to whom hepatectomy was applied in Medipol Universty of School of Medicine Department of Organ Transplantation between April 2014 and July 2015 was made. Coagulopathy was defined as prothrombin time ≥15 sec. or platelet count <80000/mm 3 on postoperative day 3. Donors were separated into 2 groups as those with (n=24) and without (n=22) coagulopathy. Preoperative, intraoperative and postoperative factors acting on coagulopathy were analyzed. Results:In the intergroup analysis, it was seen that remnant liver volume, remnant liver volume % and remnant liver volume to body weight ratio were factors associated with coagulopathy. The cut-off values for these 3 parameters were calculated as 773.5cm 3 , 40.5% and 0.915 cm 3 /kg, respectively. Only remnant liver volume % was determined as a risk factor for coagulopathy after donor hepatectomy on multiple logistic regression analysis. Conclusion:The results of this study showed that the most important risk factors affecting coagulopathy after donor hepatectomy were the parameters associated with remnant liver volume.

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“…[2,4–6] The incidence of gastrointestinal complications is also high (53%) after living donor hepatectomy (including cholecystectomy), with diarrhea being the most common symptom (31%). [7] Cholecystectomy is routinely performed at most transplant center during living donor hepatectomy.…”

Section: Introductionmentioning

confidence: 99%

Predictors of Diarrhea after Hepatectomy and Its Impact on Gastrointestinal Quality of Life in Living Donors

et al. 2016

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BackgroundDonor safety and preservation of donor health after living liver donation are of paramount importance. Diarrhea has a significant influence on gastrointestinal quality of life among donors who have undergone living donor hepatectomy. Thus, we aimed to investigate predictors of diarrhea after hepatectomy and its impact on gastrointestinal quality of life in living donors.MethodsWe retrospectively examined the medical records of 204 living liver donors who underwent hepatectomy during the period January 2010 to June 2013 at a single medical center. Diarrhea was defined as the passing of three or more liquid stools per day. The Chinese version of the Gastrointestinal Quality of Life Index (GIQLI) was used to assess the influence of diarrhea on quality of life in donors.ResultsDuring the study period, diarrhea was diagnosed in 62 (30.3%) of the 204 donors and the duration of diarrhea in the majority of them (n = 46, 74%) was <12 months. Risk factors associated with diarrhea included age [risk ratio (RR) = 0.84, 95% confidence interval (CI): 0.79–0.89, risk difference = 16%], and chronic cholecystitis (RR = 0.48, 95% CI: 0.24–0.99, risk difference = 52%). Compared to donors without diarrhea, donors with diarrhea had lower GIQLI scores in the following GIQLI domains: GI symptoms (1.8 vs. 3.6), physical function (2.1 vs. 3.5), emotional function (3.0 vs. 3.6), social function (3.3 vs. 3.7), and treatment reaction (2.6 vs. 3.7).ConclusionsOur findings show that younger donors and those without chronic cholecystitis are at increased risk for diarrhea after living donor hepatectomy and that diarrhea is associated with lower GIQLI scores after hepatectomy.

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Right Hepatic Lobe Donation: Impact on Donor Quality of Life

Cited by 23 publications

References 13 publications

Mental health status after living donor hepatectomy

Mental health status after living donor hepatectomy

Analysis of risk factors affecting coagulopathy after donor hepatectomy in a newly established liver transplant center

Predictors of Diarrhea after Hepatectomy and Its Impact on Gastrointestinal Quality of Life in Living Donors

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