Right atrial function in patients with pulmonary hypertension: A study with two-dimensional speckle-tracking echocardiography

Meng, Xiangli; Li, Yidan; Li, Hong; Wang, Yidan; Zhu, Wenzhen; Lu, Xiuzhang

doi:10.1016/j.ijcard.2017.11.093

Cited by 23 publications

(19 citation statements)

References 19 publications

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“…This might suggest a compensatory mechanism that takes place in the early stages of the disease, but once the preload reserve reaches its limit, it begins to fail. This concept is supported by the identification of an augmented RA emptying fraction in patients with mild-to-moderate PH, which decreases in severe PH, in line with the degradation of RA systolic function [53]. All these evidences suggest that RA strain might serve as a useful non-invasive parameter to evaluate the severity of PH.…”

Section: Chronic Cor Pulmonalementioning

confidence: 66%

Cor pulmonale: the role of traditional and advanced echocardiography in the acute and chronic settings

et al. 2020

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Cor pulmonale is the condition in which the right ventricle undergoes morphological and/or functional changes due to diseases that affect the lungs, the pulmonary circulation, or the breathing process. Depending on the speed of onset of the pathological condition and subsequent effects on the right ventricle, it is possible to distinguish the acute cor pulmonale from the chronic type of disease. Echocardiography plays a central role in the diagnostic and therapeutic work-up of these patients, because of its non-invasive nature and wide accessibility, providing its greatest usefulness in the acute setting. It also represents a valuable tool for tracking right ventricular function in patients with cor pulmonale, assessing its stability, deterioration, or improvement during follow-up. In fact, not only it provides parameters with prognostic value, but also it can be used to assess the efficacy of treatment. This review attempts to provide the current standards of an echocardiographic evaluation in both acute and chronic cor pulmonale, focusing also on the findings present in the most common pathologies causing this condition.

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Section: Chronic Cor Pulmonalementioning

confidence: 66%

Cor pulmonale: the role of traditional and advanced echocardiography in the acute and chronic settings

et al. 2020

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“…8,9 The group of pulmonary hypertension underwent modifications in all stages of the atrial cycle predominating in the reservoir phase, very similar to that compared with the literature. 3,8,9 Limitations of our study also included a reduced sample size, interoperator variability in estimating the pulmonary pressure, heterogeneity in etiology across patients with pulmonary hypertension, differences in population regarding sex, age and severity of the disease.…”

Section: Discussionmentioning

confidence: 99%

“…7 Another study in 60 patients with pulmonary hypertension compared against 30 healthy volunteers further proves that the reservoir function of the RA is significantly impaired. 3 An increase in pulmonary vascular resistance, dilation of the right ventricle and levels of NT-proBNP significantly correlated with poor functional class. According to the results, a strain value <38.4% predicted accurately WHO-function class >III, with a 97% sensitivity and 75% specificity.…”

Section: Figurementioning

confidence: 97%

“…These reduced reservoir volumes caused by a decrease in early diastolic emptying of right atrium may result in an increased volume at the start of right atrial systole. The average cutoff point for global longitudinal strain of the right atrium (RA) should be >38% 3 and its value has been linked with an improved five-year survival in patients with pulmonary hypertension, as well as improvement in the functional capacity, with an 86.8% sensitivity and 84% specificity. An atrial strain <25% is associated with increased mortality, according to a study with 151 patients with precapillary pulmonary hypertension.…”

Section: Figurementioning

confidence: 99%

“…If the pulmonary pressure remains elevated, structural changes begin to appear in the right atrium, modifying the atrial physiology, mainly in the reservoir phase, which contributes to a lower right ventricular output. [1][2][3] Even though the right atrial strain is not standardized yet, this measurement can be useful in patients with pulmonary hypertension. Ongoing studies are designed to establish the cut-off points, as it happened with the left atrium.…”

Section: Introductionmentioning

confidence: 99%

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Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

Sánchez-Hernández¹,

Martin²,

Larraya-Indaberea³

et al. 2019

CIU Cardiac Image Updated

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Atrial and ventricular function are closely related. Right atrial strain is currently being studied for validation. The purpose of our research is to evaluate its behavior in patients with pulmonary hypertension and compare it with healthy adults, with the hypothesis that right atrial strain would be lower in the first group. Methods: This is an observational, cross-sectional study. Only subjects with secondary pulmonary hypertension were included in the patient group. Subjects underwent systematic echocardiography with equipment from Philips (Epic 7), acquiring routine 2D images in standard and modified 4 chamber view, for assessment of right atrial function and estimated pulmonary arterial systolic pressure in both groups. The respective post-processing analysis software used was QLAB 9 (Cardiac motion quantification (CMQ)). Results: A total of 60 subjects, 30 in each group, were included. The mean age was 78 years in the pulmonary hypertension group (60% male), and 26 years in the healthy subjects (16% males). The mean pulmonary systolic pressure in the patient group was 60 mmHg (p <0.0001). Right atrial mean global longitudinal strain was 17.8% in patient group vs 44% in the control group, p <0.0001. Conclusions: The longitudinal global strain of the right atrium is significantly lower in patients with pulmonary hypertension compared against healthy subjects. The reservoir phase of the atrial cycle had the biggest difference in deformation between both groups.

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MRI Assessment of the Tricuspid Valve and Right Heart

Truong

Palmer

Tretter

et al. 2022

Tricuspid Valve Disease

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Right atrial function in patients with pulmonary hypertension: A study with two-dimensional speckle-tracking echocardiography

Cited by 23 publications

References 19 publications

Cor pulmonale: the role of traditional and advanced echocardiography in the acute and chronic settings

Cor pulmonale: the role of traditional and advanced echocardiography in the acute and chronic settings

Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

MRI Assessment of the Tricuspid Valve and Right Heart

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