Rift Valley fever virus infection : physiopathology and pathogenesis

Quellec, Jordan; Salinas, Sara; Simonin, Yannick; Cêtre-Sossah, Catherine

doi:10.1684/vir.2021.0919

Cited by 3 publications

(12 citation statements)

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“…In these animals, death can occur as soon as two days after the onset of the disease. Although they are also infected by RVFV, adult animals seem to be more resistant to the disease (20–30% mortality) [ 3 , 86 ]. RVFV replicates in the liver of animals, causing liver damage and hemorrhages resulting in bloody diarrhea [ 64 , 81 ].…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…Sheep and goats are more likely to die than cattle [ 86 , 87 ]. Cattle show less severe symptoms, with an adult mortality rate of 5–10%, but in calves, the rate varies from 10 to 70% [ 3 , 87 ]. The most striking sign during RVF epizootics is the wave of abortions that occurs in livestock, with high mortality in younger animals [ 3 ].…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…The geographical distribution of these viruses is closely linked to the distribution of their biologically competent vectors as well as to environmental and climatic factors that favor their distribution [ 2 ]. Rift Valley fever (RVF) is a zoonotic arbovirosis that mainly affects ruminant livestock but also humans [ 3 ]. The RVF virus (RVFV), an arbovirus that belongs to the family Phenuiviridae, genus Phlebovirus [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

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Rift Valley fever in West Africa: A zoonotic disease with multiple socio-economic consequences

et al. 2023

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Section: Clinical Manifestationsmentioning

confidence: 99%

Section: Clinical Manifestationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Rift Valley fever in West Africa: A zoonotic disease with multiple socio-economic consequences

et al. 2023

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“…It is a zoonotic virus that can be transmitted through infected mosquito bites to domestic livestock and close contact with sick animals cause infections in humans [ 101 ]. Infected humans generally have mild flu-like symptoms but in a small percentage of the patients, it might lead to severe disease [ 102 ]. Despite the availability of live and inactivated vaccines for ruminants, there is an urgent need for a human vaccine to prevent spread of RVFV from Africa to non-endemic areas [ 103 ].…”

Section: Ruminant Viral Diseases and Lamp Assays For Diagnosismentioning

confidence: 99%

Diagnosis of Ruminant Viral Diseases with Loop-Mediated Isothermal Amplification

2023

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Infectious diseases in livestock industry are major problems for animal health, food safety, and the economy. Zoonotic diseases from farm animals are significant threat to human population as well. These are notifiable diseases listed by the World Organization for Animal Health (OIE). Rapid diagnostic methods can help keep infectious diseases under control in herds. Loop-mediated isothermal amplification (LAMP) is a simple and rapid nucleic acid amplification method that is studied widely for detection of many infectious diseases in the field. LAMP allows biosensing of target DNA or RNA under isothermal conditions with high specificity in a short period of time. An untrained user can analyze results based on color change or turbidity. Here we review LAMP assays to diagnose OIE notifiable ruminant viral diseases in literature highlighting properties of LAMP method considering what is expected from an efficient, field usable diagnostic test.

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“…Nonstructural NS protein of RVFV was identified as a potential virulence factor that was neurotoxic and could damage brain cells 22,23 . RVFV infection can cause hepatitis, hemorrhage, and leukopenia in humans, and it could affect different tissues generally resulting in ocular and neurological pathology 24 . The pathophysiology of RVFV infection appears to be complex.…”

Section: Rvfv Diagnosis and Complicationsmentioning

confidence: 99%

Rift valley fever (RVF) viral zoonotic disease steadily circulates in the Mauritanian animals and humans: A narrative review

Mohapatra¹,

Kutikuppala

Kandi

et al. 2023

Health Science Reports

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Background and Aim Rift valley fever (RVF) virus (RVFV) is reportedly steadily circulating in Mauritania being repeated in 1987, 2010, 2012, 2015, and 2020. Mauritania seems a preferred niche for RVF virus due to its persistent outbreak there. Lately, nine Mauritanian wilayas confirmed 47 (23 fatalities with 49% CFR) human cases between August 30 and October 17, 2022. Most of the cases were largely among livestock breeders associated with animal husbandry activities. The review aimed at understanding the origin, cause, and measures to counter the virus. Methods The facts and figures from the various published articles sourced from databases including Pubmed, Web of Science, and the Scopus as also some primary data from health agencies like WHO, CDC, and so forth were evaluated and the efficacy of countermeasures reviewed. Results Among the reported confirmed cases, it was found that 3−70 year age‐group males outnumbered the females. Deaths after fever occurred primarily due to acute hemorrhagic thrombocytopenia. Human infections often occurred through zoonotic transmission mainly through mosquitoes in the population contiguous to cattle outbreak, a conducive site for local RVFV transmission. Many transmission cases were through direct or indirect contact with blood or organs of the infected animal. Conclusion RVFV infection was predominant in the Mauritanian regions bordering Mali, Senegal, and Algeria. High human and domesticated animal density as also the existing zoonotic vectors further contributed to RVF virus circulation. Mauritanian RVF infection data confirmed that RVFV was zoonotic that included small ruminants, cattle, and camel. This observation hints at the role of transborder animal mobility in RVFV transmission. In light of this, preventive approaches with effective surveillance and monitoring system following the One Health model is extremely beneficial for a free and fair healthy world for all.

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Rift Valley fever virus infection : physiopathology and pathogenesis

Cited by 3 publications

References 0 publications

Rift Valley fever in West Africa: A zoonotic disease with multiple socio-economic consequences

Rift Valley fever in West Africa: A zoonotic disease with multiple socio-economic consequences

Diagnosis of Ruminant Viral Diseases with Loop-Mediated Isothermal Amplification

Rift valley fever (RVF) viral zoonotic disease steadily circulates in the Mauritanian animals and humans: A narrative review

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