Rifampicin Loaded Spray-Dried Olibanum Gum Resin Pulmospheres for Lung Delivery

Patil, Jagadevappa; Jagadhane, V B; Jamagondi, Laxmi N; Gurav, Prashant

doi:10.22270/jddt.v0i0.884

Cited by 3 publications

(14 citation statements)

References 15 publications

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“…oil. In next step, cross linking is carried out by either of two following methods- [17][18][19][20] i. Cross linking by heat: cross linking by heat is carried out by adding the dispersion, to previously heated oil.…”

Section: Single Emulsion Techniquesmentioning

confidence: 99%

“…Heat denaturation is however, not suitable for the thermolabile drugs. [17][18][19][20] ii. Chemical cross linking: chemical cross liking is done with the help of agents such as glutraldehyde, formaldehyde, terephthaloyl chloride, diacid chloride, etc.…”

Section: Single Emulsion Techniquesmentioning

confidence: 99%

“…(figure-1). [17][18][19][20] Figure 1: Processing scheme for microspheres-preparation by single emulsion technique 15…”

Section: Single Emulsion Techniquesmentioning

confidence: 99%

“…Laser light scattering and multi size coulter counter other than instrumental methods, which can be used for the characterization of size, shape andmorphology of the microspheres. 3,17,[26][27][28][29] Electron spectroscopy for chemical analysis:…”

Section: Evaluation Of Microspheres Particle Size and Shapementioning

confidence: 99%

“…The spectra obtained using ECSA can be used to determine the surfacial degradation of the biodegradable microspheres. 3,17,[26][27][28][29] Attenuated total reflectance Fourier Transfom-Infrared Spectroscopy:…”

Section: Evaluation Of Microspheres Particle Size and Shapementioning

confidence: 99%

See 4 more Smart Citations

Microspheres: A Promising Drug Carrier

Rastogi

Shukla

Singh

et al. 2016

J. Drug Delivery Ther.

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In the current scenario of delivering therapeutic agents to the target site requires an efficient drug delivery carrier which can deliver the drug only on the site of action in a sustained and controlled manner. Among many such carriers, microspheres fulfill all the parameters for an potent drug carrier. Microspheres are defined as free flowing powders of spherical shape, consisting of proteins or synthetic polymers, which are either biodegradable or non-biodegradable in nature and ideally having a particle size ranging from 1-1000 μm. The main aim of such novel drug delivery system is to overcome the limitations of conventional dosage forms and providing more patient compliance, increase bioavailability and more specifically targeted delivery of drugs or other active agents. This review articles deals with the ideal characteristics, types, methods of preparation, their characteristics evaluation, in vitro-in vivo correlation and applications of microsphere as drug carrier. There are various methods available today for the preparation of microspheres with the goal of achieving reproducibility and consistency with good entrapment efficiency.

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Section: Single Emulsion Techniquesmentioning

confidence: 99%