Rice-Field Drowning-Associated Pneumonia in which <i>Pseudomonas</i> spp., <i>Aspergillus fumigatus</i>, and <i>Cunninghamella</i> sp. Are Isolated

Abstract

We herein report the case of an 84-year-old who developed pneumonia after drowning in a rice field. Besides Aspergillus fumigatus, many pathogens previously not reported in drowning-associated pneumonia (such as Pseudomonas fluorescens, Pseudomonas putida, Nocardia niigatensis, and Cunninghamella sp.) were isolated from his sputum. He received sulbactam/ampicillin, trimethoprim/sulfamethoxazole, voriconazole, levofloxacin and liposomal amphotericin B, but died due to respiratory failure. Because the patient had drowned in a contaminated stagnant rice field and had multiple lung cavities, zygomycosis was suspected. This report provides invaluable information for the consideration of zygomycosis after an individual drowning in a rice field, even in an immunocompetent patient.

Pneumonia caused by Pseudomonas fluorescens: a case report

“…P. fluorescens is significantly less virulent than P. aeruginosa and is a rare cause of invasive hospital-acquired infections, with most common site of infection being the bloodstream [ 4 – 15 ]. It has been isolated in respiratory samples from patients with lung transplants [ 16 – 18 ], ventilator-associated pneumonia (VAP) [ 19 ], cystic fibrosis (CF) [ 20 – 22 ] and rice-field drowning-associated pneumonia [ 23 ].…”

The Neurotropic Black Yeast Exophiala dermatitidis Induces Neurocytotoxicity in Neuroblastoma Cells and Progressive Cell Death

“…After the initial infections, the fungi can spread via the haematogenous route. Fungal infections of the central nervous system occur either indirectly via lungs or paranasal sinuses, for example, after near-drowning episodes [42][43][44][45], via ocular orbits, and mastoid region of the temporal bone or retropharyngeal area, or directly as a consequence of trauma, invasive treatments, or brain surgery [41]. The potential mechanism of invasion of E. dermatitidis and other neurotropic fungi via the peripheral nervous system has not yet been described, nor have the mechanisms contributing to the spread of fungal infections to the brain.…”

Rare occurrence of pulmonary coinfection involving Aspergillus fumigatus and Nocardia cyriacigeorgica in immunocompetent patients based on NGS: A case report and literature review

“…[ 30 ] Such cases were also observed in nonimmunosuppressed hosts, including patients with diabetes, [ 28 ] allergic disorders, [ 26 ] bronchial thermoplasty therapy [ 27 ] ulcerative colitis during golimumab therapy, [ 23 ] and even accidental drowning incidents. [ 17 , 22 ] Pulmonary involvement was universal across all patients, while infection was also identified in subcutaneous tissues, the lymph nodes, and intracranial and central nervous system sites. A majority (60%) of the patients demonstrated a substantial recovery posttreatment.…”

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