Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins
Robert Njenga,
Julian Boele,
Friedel Drepper
et al.
Abstract:Ribosome hibernation is a commonly used strategy that protects ribosomes under unfavorable conditions and regulates developmental processes. Multiple ribosome-hibernation factors have been identified in all domains of life, but due to their structural diversity and the lack of a common inactivation mechanism, it is currently unknown how many different hibernation factors exist. Here, we show that the YqjD/ElaB/YgaM paralogs, initially discovered as membrane-bound ribosome binding proteins in E. coli, constitut… Show more
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