Riboflavin-ultraviolet-A-induced collagen cross-linking treatments in improving dentin bonding

Chiang, Yung Show; Chen, Yuh Ling; Chuang, Shu Fen; Wu, Ching Ming; Wei, Pal Jen; Han, Chang Fu; Lin, Jui Che; Chang, Hsiu‐Hua

doi:10.1016/j.dental.2013.03.015

Cited by 58 publications

(64 citation statements)

References 42 publications

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“…In contrast to the current results, some previous studies stated that dentin surface preparation with RF/UVA increased the µTBS values immediately and after water storage (9, 30). They attributed this increase in bond strength to the stiffness of dentin collagen matrix (9,30,32), upstanding of collagen fibrils and enhanced resin infiltration following cross-linking (30), decreased activity of MMPs due to increased cross linking of dentin collagen (9,29) and direct cross linking of MMPs (9). The difference between the current results and those of previous studies may be explained as follows:…”

Section: Discussioncontrasting

confidence: 56%

“…However, these limited findings may serve as a foundation for future studies of Riboflavin as an adjunctive dentin bonding treatment (30).…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have reported that light-activated riboflavin can efficiently protect the resin-dentin interface by improving the collagen properties and inhibiting MMPs (2,30,32).…”

Section: Discussionmentioning

confidence: 99%

“…Riboflavin solution was added to 1.5mg/mL bovine collagen (Sigma Aldrich, St. Louis, MO, USA) (30). The cross linking effect of riboflavin solution on type I collagen was assessed using SDS-PAGE; 0.1% riboflavin solution was prepared by dissolving riboflavin-5-phosphate (Sigma Aldrich, St. Louis, MO,USA) in distilled water.…”

Section: Methodsmentioning

confidence: 99%

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The Efficacy of Riboflavin for Collagen Cross-Linking and Optimizing the Bond Strength of an Etch and Rinse Adhesive System to Dentin

Kasraei¹,

Malek²,

Khamverdi³

et al. 2017

Avicenna J Dent Res

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Background and Objectives: Previous studies have shown that increasing collagen resistance to degradation stabilizes the resindentin interface and collagen cross-linkers can prevent the degradation of collagen fibrils as such. This study sought to assess the efficacy of light-activated riboflavin for collagen cross-linking and optimizing the micro tensile bond strength (µTBS) of an etch and rinse adhesive system to dentin. Methods: Occlusal surfaces of 12 sound premolars were ground in order to expose dentin. The teeth were randomly divided into two groups. Adper single bond was applied on etched dentin and light cured in the control group and Composite was then applied. In the test group, all the steps were done in a similar manner to the control group with the difference that after acid etching, 0.1% riboflavin solution was applied on dentin surface and was activated by blue light irradiation for 2 minutes. After thermocycling, the teeth were sectioned in 2 directions in such a way that 14 resin-dentin sticks with 1 mm2 cross-section were prepared in each

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Section: Discussioncontrasting

confidence: 56%

“…However, these limited findings may serve as a foundation for future studies of Riboflavin as an adjunctive dentin bonding treatment (30).…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have reported that light-activated riboflavin can efficiently protect the resin-dentin interface by improving the collagen properties and inhibiting MMPs (2,30,32).…”

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

The Efficacy of Riboflavin for Collagen Cross-Linking and Optimizing the Bond Strength of an Etch and Rinse Adhesive System to Dentin

Kasraei¹,

Malek²,

Khamverdi³

et al. 2017

Avicenna J Dent Res

View full text Add to dashboard Cite

show abstract

“…This was attributed to the presence of active groups in plasma, such as UV, electrons, and radicals. Many previous studies have reported that UV exposure could lead to gelatin intermolecular crosslinking 26) and, possibly, to the formation of radicals on the aromatic amino acids, such as tyrosine and phenylalanine, in collagen and gelatin 27,28) . The electrons of plasma may interact with polymers to induce the formation of radicals in the polymeric collagen fibers to promote crosslinking 29) .…”

Section: Discussionmentioning

confidence: 99%

Effects of a modified cold atmospheric plasma jet treatment on resin-dentin bonding

Zhu

Zhou

Guo

et al. 2018

Dental Materials Journal

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The radio-frequency atmospheric-pressure glow discharge (RF-APGD) plasma is a novel cold atmospheric plasma (CAP) source, which has low energy characteristic. This study investigated the effect of RF-APGD plasma on the mechanical properties of dentin collagen and resin-dentin bonding. The scanning electron microscopy analysis was performed before and after a novel RF-APGD plasma and a conventional CAP treatment and a tensile test was carried out for the stiffness of dentin collagen. The microtensile resin-dentin bond strength was tested either immediately or after a 50,000-cycle thermocycling process. Dentin collagen maintained an intact structure after a 45-s RF-APGD plasma treatment, whereas even a 10-s treatment with the conventional CAP collapsed the collagen scaffold. When compared with control groups, the RF-APGD plasma treatment showed: (i) an improved stiffness of dentin collagen; (ii) a significant improvement in the bonding strength before/after artificial aging. Thus, RF-APGD plasma treatment has excellent prospects as a resin-dentin bonding protocol.

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Photoactivated rose bengal‐doped TiO₂ nanoparticles modified fifth‐generation adhesive on the survival rate of Streptococcus mutants and mechanical properties of tooth‐colored restorative material to carious dentin

Alanazi,

Khan,

Siddiqui

et al. 2024

Microscopy Res & Technique

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Assessment of the antimicrobial, micro tensile bond strength (μTBS), and degree of conversion (DC) of fifth‐generation adhesive modified using photoactivated 0.5% rose bengal (RB) and photoactivated RB‐doped titanium dioxide nanoparticles (TiO2NPs) in different concentrations (2% and 5%) as compared with the unmodified adhesive bonded to the carious affected dentin (CAD). Forty mandibular molars with caries progression up to the middle third of the dentin, as per the International Caries Detection and Assessment System (ICDAS) score of 4 and 5 were included. Specimens were divided into four groups based on etch and rinse adhesive (ERA) modification group 1: unmodified ERA, group 2: photoactivated 0.5% RB photosensitizer (PS) modified ERA, group 3: photoactivated RB‐doped 2 wt% TiO2NPs adhesive, group 4: photoactivated RB‐doped 5 wt% TiO2NPs adhesive. Followed by adhesive and composite restoration on the CAD surface. All the specimens were thermocycled and an assessment of μTBS and failure pattern analysis was performed. The antibacterial potency of RB and RB‐doped TiO2NPs (2% and 5%) followed by their activation using visible light against Streptococcus mutans (S.mutans) were tested. The survival rate of S.mutans was assessed using the Kruskal–Wallis test. The analysis of μTBS involved the use of ANOVA, followed by a post‐hoc Tukey honestly significant difference (HSD) multiple comparisons test. Group 1 (Unmodified ERA) (0.52 ± 0.31 CFU/mL) treated samples unveiled the highest means of bacterial survival and lowest μTBS (11.32 ± 0.63 MPa). Nevertheless, group 4: photoactivated RB‐doped 5 wt% TiO2NPs adhesive displayed the lowest outcomes of S.mutans survival (0.11 ± 0.02 CFU/mL) and highest bond strength (18.76 ± 1.45 MPa). The photoactivated RB‐doped 2 wt% TiO2NPs in adhesive demonstrated promising enhancements in both μTBS and antibacterial efficacy against S.mutans. However, it is noteworthy that this modification led to a decrease in the DC of the adhesive.Research Highlights Unmodified ERA‐treated samples unveiled the highest bacterial survival and the lowest μTBS. Photoactivated RB‐doped 5 wt% TiO2NPs adhesive displayed the lowest S.mutans survival rate and highest bond strength. DC decreased with an increase in concentration of TiO2.

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Riboflavin-ultraviolet-A-induced collagen cross-linking treatments in improving dentin bonding

Cited by 58 publications

References 42 publications

The Efficacy of Riboflavin for Collagen Cross-Linking and Optimizing the Bond Strength of an Etch and Rinse Adhesive System to Dentin

The Efficacy of Riboflavin for Collagen Cross-Linking and Optimizing the Bond Strength of an Etch and Rinse Adhesive System to Dentin

Effects of a modified cold atmospheric plasma jet treatment on resin-dentin bonding

Photoactivated rose bengal‐doped TiO₂ nanoparticles modified fifth‐generation adhesive on the survival rate of Streptococcus mutants and mechanical properties of tooth‐colored restorative material to carious dentin

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Riboflavin-ultraviolet-A-induced collagen cross-linking treatments in improving dentin bonding

Cited by 58 publications

References 42 publications

The Efficacy of Riboflavin for Collagen Cross-Linking and Optimizing the Bond Strength of an Etch and Rinse Adhesive System to Dentin

The Efficacy of Riboflavin for Collagen Cross-Linking and Optimizing the Bond Strength of an Etch and Rinse Adhesive System to Dentin

Effects of a modified cold atmospheric plasma jet treatment on resin-dentin bonding

Photoactivated rose bengal‐doped TiO2 nanoparticles modified fifth‐generation adhesive on the survival rate of Streptococcus mutants and mechanical properties of tooth‐colored restorative material to carious dentin

Contact Info

Product

Resources

About

Photoactivated rose bengal‐doped TiO₂ nanoparticles modified fifth‐generation adhesive on the survival rate of Streptococcus mutants and mechanical properties of tooth‐colored restorative material to carious dentin