Riboflavin immobilized Fe
 3
 O
 4
 magnetic nanoparticles carried with
 n
 -butylidenephthalide as targeting-based anticancer agents

Wu, Ching; Chen, Yu-Chie

doi:10.1080/21691401.2018.1548473

Cited by 26 publications

(13 citation statements)

References 47 publications

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“…The utilization of SPIONs is broadly applied as a drug delivery agent or carrier in carcinoma therapeutic purpose. Iron oxide based MNPs were long exercised for different biomedical functions including drug carriers, magnetic hyperthermia, MRI imaging and cancer therapeutic agents in lung cancer [83][84][85][86]. The implication of iron oxide based MNPs has currently been demonstrated by Wang et al, in MRI and ultrasound ablation therapy as shown in Figure 3 [83].…”

Section: Drug Deliverymentioning

confidence: 99%

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Rastogi¹,

Pandey²,

Pk³

et al. 2021

Preprint

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There are numerous challenges involved in the diagnosis and treatment of lung cancer. Globally, majority of people suffers from cancerous disease involving throat cancer, lung cancer, stomach cancer, cancerous brain tumor. Among these the most common ones is the lung cancer or lung carcinoma. The leading cause of the lung cancer is the smoking. Around 80% to 90% of deaths are caused due to Non-small cell lung cancer (NSCLC). The inadequate diagnostic techniques and low chances for the survival of lung cancer patients results from the lack of an early prognosis and incompetency in traditional therapies. However, such challenges involved in the prognosis and treatment of lung cancer are on decline with the progression in magnetic nanoparticle (MNP) technology. Many break-through discoveries and inventions have been made in the field of cancer therapy by using magnetic nanoparticles. The implication of nanotechnology has led to the recent advancement in nanomedicine field. This has encouraged the improvement in different therapeutic and diagnosis strategies employing nanotechnology. The generation of immense technological benefits for nanoparticles systems has been accredited to its remarkable nanoscale physico-chemical properties. This in turns provides the early detection of lung cancer and active drugs delivery for an improved theranostics strategy. The present review provides a general idea of the current progression in the therapeutic and prognosis purpose of magnetic nanoparticles. Further, we disclose the development in the lung cancer theranostics by functionalization of magnetic nanoparticles. The established importance of magnetic nanoparticles in the theranostics centers for lung cancer has been revealed in this paper. The challenges existing in the theranostics of lung cancer are addressed through the functioning of magnetic nanoparticles in the process.

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Section: Drug Deliverymentioning

confidence: 99%

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Rastogi¹,

Pandey²,

Pk³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…The results demonstrated that the as-prepared functional MNPs can be used to effectively target and inhibit the cell growth, have no toxicity toward non-targeted cells, and have the potential to be used as anti-cancer agents. More in vivo tests must be further performed in order to assess the clinical relevance of this approach [87].…”

Section: Drug Deliverymentioning

confidence: 99%

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

2019

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During the last few decades, magnetic nanoparticles have been evaluated as promising materials in the field of cancer detection, screening, and treatment. Early diagnosis and screening of cancer may be achieved using magnetic nanoparticles either within the magnetic resonance imaging technique and/or sensing systems. These sensors are designed to selectively detect specific biomarkers, compounds that can be related to the onset or evolution of cancer, during and after the treatment of this widespread disease. Some of the particular properties of magnetic nanoparticles are extensively exploited in cancer therapy as drug delivery agents to selectively target the envisaged location by tailored in vivo manipulation using an external magnetic field. Furthermore, individualized treatment with antineoplastic drugs may be combined with magnetic resonance imaging to achieve an efficient therapy. This review summarizes the studies about the implications of magnetic nanoparticles in cancer diagnosis, treatment and drug delivery as well as prospects for future development and challenges of magnetic nanoparticles in the field of oncology.

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“…The BP‐Fe 3 O 4 @RFMP MNPs did not show any significant adverse effects on non‐target cells. The cell viability was two times lower by the use of Fe 3 O 4 @RFMP MNPs immobilised with BP than by the use of freeform BP at the same concentration [102].…”

Section: Application Of Hybrid Nps Against Different Type Of Cancersmentioning

confidence: 99%

Surface‐functionalised hybrid nanoparticles for targeted treatment of cancer

Tariq

Bokhari

2020

IET nanobiotechnol.

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Riboflavin immobilized Fe ₃ O ₄ magnetic nanoparticles carried with n -butylidenephthalide as targeting-based anticancer agents

Abstract: (2019) Riboflavin immobilized Fe 3 O 4 magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents, Artificial

Cited by 26 publications

References 47 publications

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

Surface‐functionalised hybrid nanoparticles for targeted treatment of cancer

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Riboflavin immobilized Fe 3 O 4 magnetic nanoparticles carried with n -butylidenephthalide as targeting-based anticancer agents

Abstract: (2019) Riboflavin immobilized Fe 3 O 4 magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents, Artificial

Cited by 26 publications

References 47 publications

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

The Advancement in Magnetic Nanoparticles for the Diagnosis of Lung Cancer and Its Monitoring

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

Surface‐functionalised hybrid nanoparticles for targeted treatment of cancer

Contact Info

Product

Resources

About

Riboflavin immobilized Fe ₃ O ₄ magnetic nanoparticles carried with n -butylidenephthalide as targeting-based anticancer agents