Rib development in chick embryos analyzed by means of tantalum foil blocks

Sweeney, Robert M.; Watterson, Ray L.

doi:10.1002/aja.1001260202

Cited by 35 publications

(16 citation statements)

References 9 publications

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“…Placement of a foil barrier between the somites and LPM at forelimb levels blocks wing bud formation (Murillo-Ferrol, 1965;Sweeney and Watterson, 1969;Stephens and McNulty, 1981). Equivalent experiments placing a foil barrier between LPM and somites at hindlimb levels has not been reported and, therefore, whether axial tissues are the source of an inductive signal required for hindlimb initiation remains an open question that should be addressed in the future.…”

Section: Retinoic Acid Is Required For Limb Bud Initiationmentioning

confidence: 99%

Regulation of limb bud initiation and limb‐type morphology

Duboc¹,

Logan²

2011

Developmental Dynamics

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While the paired forelimb and hindlimb buds of vertebrates are initially morphologically homogeneous, as the limb progenitors differentiate, each individual tissue element attains a characteristic limb-type morphology that ultimately defines the constitution of the forelimb or hindlimb. This review focuses on contemporary understanding of the regulation of limb bud initiation and formation of limb-type specific morphologies and how these regulatory mechanisms evolved in vertebrates. We also attempt to clarify the definition of the terms limb-type identity and limb-type morphology that have frequently been used interchangeably. Over the last decade, three genes, Tbx4, Tbx5, and Pitx1, have been extensively studied for their roles in limb initiation and determining limb-type morphologies. The role of Tbx4 and Tbx5 in limb initiation is clearly established. However, their putative role in the generation of limb-type morphologies remains controversial. In contrast, all evidence supports a function for Pitx1 in determination of hindlimb morphologies.

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Section: Retinoic Acid Is Required For Limb Bud Initiationmentioning

confidence: 99%

Regulation of limb bud initiation and limb‐type morphology

Duboc¹,

Logan²

2011

Developmental Dynamics

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“…These turtle-specific features of Myf5 would possibly explain not only the turtle-specific morphology of the muscle plate (Ohya et al 2006) but also truncation of the ribs. Vertebrate ribs develop from somites (Seno 1961;Pinot 1969;Sweeney and Watterson 1969;Christ et al 1974;Christ and Wilting 1992;Huang et al 1994Huang et al , 1996Huang et al , 2000aKato and Aoyama 1998;Evans 2003). The proximal rib, consisting of the costal head, neck and tubercle (Huang et al 2000a), is derived from ventromedial part of sclerotome ( Fig.…”

Section: Carapace Development and Evolutionary Scenarios For Turtlesmentioning

confidence: 96%

“…The rib progenitor cells or syndetomal cells developed in the axial domain extend secondarily into the lateral body wall along with the myotomal cells to form the most distal part of the ribs: the sterno-distal ribs in case of chicken (Aoyama et al 2005) and its associated intercostal muscles (Sweeney and Watterson 1969;Christ et al 1983;Sudo et al 2001;Wang et al 2005). Though the molecular basis of this penetration is not yet well understood (Sudo et al 2001), Hox genes Top During early development, myoblasts appearing in the rostral and caudal edge of myotomes (me) induce a syndetome (sy) in the intersomitic region of lateral sclerotome (green), in which distal rib (rd) progenitors are contained.…”

Section: Carapace Development and Evolutionary Scenarios For Turtlesmentioning

confidence: 99%

Body plan of turtles: an anatomical, developmental and evolutionary perspective

et al. 2011

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The evolution of the turtle shell has long been one of the central debates in comparative anatomy. The turtle shell consists of dorsal and ventral parts: the carapace and plastron, respectively. The basic structure of the carapace comprises vertebrae and ribs. The pectoral girdle of turtles sits inside the carapace or the rib cage, in striking contrast to the body plan of other tetrapods. Due to this topological change in the arrangement of skeletal elements, the carapace has been regarded as an example of evolutionary novelty that violates the ancestral body plan of tetrapods. Comparing the spatial relationships of anatomical structures in the embryos of turtles and other amniotes, we have shown that the topology of the musculoskeletal system is largely conserved even in turtles. The positional changes seen in the ribs and pectoral girdle can be ascribed to turtle-specific folding of the lateral body wall in the late developmental stages. Whereas the ribs of other amniotes grow from the axial domain to the lateral body wall, turtle ribs remain arrested axially. Marginal growth of the axial domain in turtle embryos brings the morphologically short ribs in to cover the scapula dorsocaudally. This concentric growth appears to be induced by the margin of the carapace, which involves an ancestral gene expression cascade in a new location. These comparative developmental data allow us to hypothesize the gradual evolution of turtles, which is consistent with the recent finding of a transitional fossil animal, Odontochelys, which did not have the carapace but already possessed the plastron.

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“…This aids conceptualization of the 'metamorphosis' from embry onic continuous distribution of axial skeletal substrate to the discrete segmental distribution of the later fetus; (2) there is a persistent argument (Strauss and Rawles, 1953;Sweeney andWaterson, 1969\ Kieny et al, 1972;Seno, 1961;Pinot, 1969) as to whether the rib is formed from two separate embryonic tissues, the sclerotome or somitic mesoderm posteriorly and the laternal plate mesoderm anteriorly. This has important ramifications for the consideration of inductive influences.…”

Section: Discussionmentioning

confidence: 99%

Rib Anomalies in Myelodysplasia

McLennan¹

1976

Neonatology

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An embryologic teratogenic mechanism is reconstructed by utilizing the distribution of anomalous ribs in children with lumbosacral myelomeningocele. This methodology may help to coalesce information from experimental models of teratogenesis and from descriptive human embryology. It provides an approach to deductive reasoning about human structural anomalies based on dynamic embryonic models of teratogenesis. Availability of a developmental time scale, based for example on the distribution of defective ribs, may be useful in the study of other teratogenic and developmental processes.

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Rib development in chick embryos analyzed by means of tantalum foil blocks

Cited by 35 publications

References 9 publications

Regulation of limb bud initiation and limb‐type morphology

Regulation of limb bud initiation and limb‐type morphology

Body plan of turtles: an anatomical, developmental and evolutionary perspective

Rib Anomalies in Myelodysplasia

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