Riachin, a new cyanoglucoside from Bauhinia pentandra and its antioxidant activity

Estudo Taxonômico das subfamílias Cercidoideae e Detarioideae (Leguminosae) no Parque Ecológico Engenheiro Ávidos, Sertão Paraibano

“…Considerações: Bauhina pentandra é encontrada na Caatinga e em ambientes de transição entre Caatinga e Cerrado, sobre solos arenosos, pedregosos ou argilosos (Vaz & Tozzi 2005;Queiroz 2009). É considerada uma espécie forrageira para alimentação de bovinos, estudos químicos evidenciam seu potencial como antifúngico e antioxidante (Vaz & Tozzi 2005;Queiroz 2009;Silva et al 2013;Conceição 2015). Distinguível de B. cheilantha por apresentar ramos armados, folhas profundamente lobadas, pétalas lineares e androceu com 5 estames férteis e 5 estaminódios.…”

Modern strategy for new medicine research: study of pharmacological activities of riachin, a non-cyanogenic cianoglycoside extracted from Bauhinia pentandra

“…To facilitate the evaluation of the data, the molecular structure of Riachin was presented as being obtained by SMILE PubChem software, available in https://pubchem.ncbi.nlm.nih.gov/search/search. cgi#, resulting in the representative: C2 (C (O [H @ H] 1C (C = CC (C1O) O) N = CC #) OC (C (C2O) O) CO) O, with substituents in position 4 described in Figure 2 [10].…”

“…Recently, investigation of root bark of B. pentandra (Fabaceae) led to the isolation and characterization of a new cianoglicosídeo has been termed Riachin. Preliminary studies have demonstrated antioxidant activity in tests 2,2-diphenyl-1-picrylhydrazyl (2,2-diphenyl-1-picrylhydrazyl, DPPH) and 2.20-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid) [2,2-azino-bis (ethylbenzo thiazoline--6-sulfonic acid) diammonium salt, ABDS], in addition to displaying chelating activity of metals to ferrous ions (Fe 2+) [10]. However, such studies are very recent and there is still much to be learned about the said cianoglicosídeo.…”

7-epi-griffonilide, a new lactone from Bauhinia pentandra: complete 1H and 13C chemical shift assignments

“…It consists of about 300 species, distributed in most tropical countries, including Africa, Asia and America (Cechinel Filho 2009). Previous phytochemical studies with plants from Bauhinia genus report the presence of lactones, flavonoids, terpenoids, steroids, triterpenes, tannins, quinones and alkaloids Cechinel Filho 2002, Maia Neto et al 2008), while studies from B. pentandra reported the chemical composition of the essential and fatty oils (Duarte-Almeida et al 2004, Almeida et al 2015, as well as the isolation of flavonoids (Salatino et al 1999) and cyanoglucosides (Silva et al 2013). In this paper, we report the isolation and structure elucidation of lactones (1 and 2), phenylacetic derivatives (3a, 3b and 3c) and a mixture of cyanoglucoside (4a) and glucopyranoside (4b).…”