Rhodium(iii)-catalyzed oxidative annulation ofN-arylbenzamidines with maleimidesviadual C–H activation

Abstract

An oxidative annulation of N-arylbenzimidamide with maleimides has been developed for the first time using a catalytic amount of [Cp*RhCl2]2 complex for the synthesis of a diverse range of 1H-benzo[4,5]imidazo[2,1–a]pyrrolo[3,4-c]isoquinoline-1,3(2H)-dione...

Rh(III)‐Catalyzed C−H Annulation and Spirolactonization of 2‐Aryl‐1H‐benzo[d]imidazoles with 4‐Hydroxy‐2‐alkynoates via C−H bond activation

“…Following our interest on transition metal catalyzed CÀ H functionalization of aromatic systems, [15] we herein report a novel annulation process for the synthesis of 2',2 5]imidazo[2,1-a]isoindole-11,3'-furan]-5'(4'H)-one and 1,1-dimethylbenzo [4,5]imidazo[2,1-a]furo[3,4c]isoquinoline-3(1H)-one frameworks. Initially, the reaction was conducted using different catalysts, additives in various solvents (Table 1).…”