“…In this case, the coaxial flow can be generated and form the through hole in the fiber. Microchip method can also form the coaxial flow via turning the heights of different channels similar to the nested capillaries method, but have many advantages, including adjustable diameter and complex microstructure of fibers (Kang et al., 2011, 2012; Yao et al., 2020), biocompatibility (Elkhoury et al., 2021; Nie & Takeuchi, 2018; Yu et al., 2014) and easy to mix extra materials (cytokines (Heinrich et al., 2019), particles (Hu et al., 2016; Ji et al., 2020; Liang et al., 2020), dyes etc.). These advantages allow these microfibers to be used in tissue engineering, drug delivery, and regenerative medicine.…”