Rhinoscleroma in a 5-year-old Portuguese Child

Simão, Inês; Gaspar, Iuri; Faustino, Rosário; Brito, Maria João

doi:10.1097/inf.0000000000000263

Cited by 6 publications

(4 citation statements)

References 8 publications

(17 reference statements)

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“…11,13,14,20 It seems that a biopsy with microbiological scrubs are the most accurate factors for identifying RS. [2][3][4]19 A careful clinical examination should always be performed. In the most severe cases, tumor tissue mass adhesion to the soft palate and the posterior pharyngeal wall was reported.…”

Section: Discussionmentioning

confidence: 99%

“…Other findings should include: nasal polyposis, extranodal Rosai-Dorfman disease, vasculitis, paracoccidioidomycosis, cocaine-induced midline destructive erosions, foreign body granulomas, or others. 2,8 In the cases of chronic growth, early stages of the disease are not clear and mostly underestimated or neglected. Slowly growing masses with progressive symptoms arising from the surrounding anatomical area of the respiratory tract should be carefully evaluated and never neglected.…”

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confidence: 99%

“…Other reports rarely explain its occurrence in Europe. [1][2][3] The most common geographical occurrence sites for this disease are South America, India, south-eastern Asia and Africa. Most studies report an overall higher occurrence in women than in men, with the age ratio being about 15-35 years.…”

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confidence: 99%

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Difficulties in diagnosing and treating nasal rhinoscleroma: A case study

Poniatowski¹,

Łuczak²,

Nelke³

2017

Dent. Med. Probl.

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For many years scleroma was considered to be a neoplastic tumor. First findings of this disease came from the 4 th century. In the 18 th century it was also called the leprosy of the nose. In 1840, a Polish surgeon was the first in the world to describe rhinoscleroma as a "chronic nose cancer". In late 1877, Jan Mikulicz-Radecki classified this scleroma as rhinoscleroma, an inflammatory disease with the most common occurrence in the nasal cavity. Because of very rare cases of this disease reported nowadays (endemic), its treatment is challenging. The disease manifests itself as a symptomatic mass causing mostly an obstruction of nasal breathing or even local nose bleeds, and infiltrates the surrounding structures of the nose and sinuses. Difficult accurate clinical diagnosis of this disease seems to be the main problem in its early detection and treatment. Apart from a surgical excisional biopsy or more radical surgical approach, additional antibiotic treatment, along with routine checkups by an infectious diseases specialist, should be maintained.A very rare and unusual case of a 75-year-old retired otolaryngologist diagnosed with a symptomatic mass in the nasal cavity, treated previously by unknown methods and without any success, will be presented. It is worth noticing that either the patient's economic status or his past job as an otolaryngologist might be related to the occurrence of rhinoscleroma as the possible route of infection.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Difficulties in diagnosing and treating nasal rhinoscleroma: A case study

Poniatowski¹,

Łuczak²,

Nelke³

2017

Dent. Med. Probl.

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“…Only a few cases have been reported in Western Europe during the past 15 years (de Pontual et al, 2008), showing a progressive reduction of incidence of RS in this geographical area. Sardinia, an Italian island where RS have been extensively reported in the past, had the highest number of cases, followed by Spain (Fernandez-Vozmediano et al, 2004), Switzerland (Nayak et al, 2015) , Germany (Paul et al, 1993), France (Botelho-Nevers et al, 2007;de Pontual et al, 2008), Portugal (Simao et al, 2014) , and United Kingdom (Hart and Rao, 2000).…”

Section: Geographical and Genetic Evidencesmentioning

confidence: 99%

Social geography of Rhinoscleroma and qualitatively and quantitatively abnormal cell-mediated immunity

Fusconi

Greco

Cattaneo

et al. 2018

Infection, Genetics and Evolution

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Rhinoscleroma is a progressive chronic granulomatous disease of the upper respiratory tract that may extend to the tracheobronchial tract. It is common belief that the pathology is determined by Klebsiella Rhinoscleromatis. In the authors' opinion, the infection with Klebsiella Rhinoscleromatis may not represent the only etiopathogenic factor of the disease. Rhinoscleroma is reported in many countries, but has a peculiar social and geographic distribution, in that it assumes an endemic character only in some regions of the Middle East, West Russia, North Africa, Indonesia, Central and South America. In Europe, most of the cases are reported in Poland, Hungary and Romania. In Italy, Rhinoscleroma is almost exclusively located in the southern and island regions. Rhinoscleroma is predominantly reported in rural areas, in the presence of poor socio-economic conditions, which according to many authors would be a co-factor triggering the disease. In this article, the authors review some inconsistencies in etiology, histology and epidemiology of Rhinoscleroma. Based on the overall picture, they propose that intrinsic factors, possibly of genetic origin, may give rise to the disease, and suggest possible lines of research to distinguish between extrinsic and intrinsic factors as determinants for Rhinoscleroma.

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Sinonasal Tract: Nonneoplastic

Brandwein

2016

Textbook of Head and Neck Pathology

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Rhinoscleroma in a 5-year-old Portuguese Child

Cited by 6 publications

References 8 publications

Difficulties in diagnosing and treating nasal rhinoscleroma: A case study

Difficulties in diagnosing and treating nasal rhinoscleroma: A case study

Social geography of Rhinoscleroma and qualitatively and quantitatively abnormal cell-mediated immunity

Sinonasal Tract: Nonneoplastic

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