Rhinocerebral Mucormycosis Complicated by Bacterial Brain Abscess

Cano, Patricia; Horseman, Michael A.; Surani, Salim

doi:10.1097/maj.0b013e3181f0aad1

Cited by 8 publications

(8 citation statements)

References 19 publications

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“…In total, 210 case reports were identified from the literature search and reviewed, of which 175 contained sufficient clinical data to be analysed. These were derived from a total of 140 papers (some papers contained multiple case reports) . Larger case series were usually excluded due to a lack of chronological data (refer to Figure for PRISMA flow diagram).…”

Section: Resultsmentioning

confidence: 99%

A meta‐analysis of survival factors in rhino‐orbital‐cerebral mucormycosis—has anything changed in the past 20 years?

Vaughan

Bartolo

Vallabh

et al. 2018

Clinical Otolaryngology

101

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Section: Resultsmentioning

confidence: 99%

A meta‐analysis of survival factors in rhino‐orbital‐cerebral mucormycosis—has anything changed in the past 20 years?

Vaughan

Bartolo

Vallabh

et al. 2018

Clinical Otolaryngology

101

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“…Risk factors for the disease include diabetes mellitus, leukemia, blood dyscracias, immunesuppressive conditions such as Graft versus host diseases etc [ 9 ]. It may also manifest in immu¬no competent persons [ 10 ]. Its occurrence in diabetic patients can be attributed to that fact that low ph or the acidosis, hyperglycemic state.…”

Section: Discussionmentioning

confidence: 99%

Mucormycosis in a surgical defect masquerading as osteomyelitis: a case report and review of literature

et al. 2016

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Mucormycosis is a rare, highly lethal opportunistic fungal disease affecting immune compromised and diabetic patients. Mucormycosis is considered as the 3rd most common invasive mycosis after candidiasis and aspergillosis in debilitating patients. It is caused by the filamentous fungi of the class zygomycetes. The infection usually begins in the nose due to inhalation of fungal spores. This fatal fungal disease needs a prompt and early definitive diagnosis, aggressive surgical therapy and high dose anti-fungal therapy. Here, we present a case report of Mucormycosis in a 64 year elderly diabetic male patient who was previously operated for myiasis and also the extensive review of the literature of the mucormycosis.

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“…This disease generally seen in people with malignant blood diseases, diabetes, organ transplantation and long term use of antibiotics, hormones, immunosuppressant. But a recent epidemiological study found that 19.16% of cases of mucormycosis occurred in patients with “no underlying disease” ( 6 ). This patient was a healthy adult before the onset of the disease and did not have any of the above risk factors.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Diagnostic Value of Metagenomics Next Generation Sequencing in Intracranial Infection Caused by Mucor

et al. 2021

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mNGS(metagenomics Next Generation Sequencing), as a novel culture-independent approach, demonstrated the capability of rapid, sensitive, and accurate pathogen identification. At present, there have been many case reports about the use of mNGS to assist in the diagnosis of bacterial, fungal, viral and parasitic infections and to guide clinicians to determine appropriate treatment. However, the clinical understanding of this technique is not comprehensive, and the experience of using it is relatively limited. We reported a 53-year-old man who was admitted to hospital with a high fever and headache. His inflammatory biomarkers were markedly elevated. Based on the clinical presentation, He was initially diagnosed as having an intracranial infection of unknown etiology and received empirical antibiotics and systemic supportive treatment. But these did not relieve his symptoms. Both the blood and CSF specimens were examined using traditional culture, serological testing, and mNGS. Traditional culture and serological testing produced negative results, while the mNGS revealed the presence of a potential pathogen, mucor, in the CSF specimen. Then targeted antifungal treatment was selected quickly and his temperature gradually returned to normal. Thus, we report the case in which mNGS was an auxiliary method to diagnose mucormycosis, and discuss this case in combination with relevant literature, in order to improve the clinical cognition of this technology.

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Rhinocerebral Mucormycosis Complicated by Bacterial Brain Abscess

Cited by 8 publications

References 19 publications

A meta‐analysis of survival factors in rhino‐orbital‐cerebral mucormycosis—has anything changed in the past 20 years?

A meta‐analysis of survival factors in rhino‐orbital‐cerebral mucormycosis—has anything changed in the past 20 years?

Mucormycosis in a surgical defect masquerading as osteomyelitis: a case report and review of literature

Case Report: Diagnostic Value of Metagenomics Next Generation Sequencing in Intracranial Infection Caused by Mucor

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