Rheumatology and osteoporosis (RETOSS): a vision of postmenopausal osteoporosis in rheumatology departments throughout Spain

Questioning vitamin D status of elderly fallers and nonfallers: a meta‐analysis to address a ‘forgotten step’

“…The proportion of fallers amongst participants with 25OHD <10, <20 and <30 ng mL −1 was between 38% and 53% , 24% and 35% , and 23% and 32% , respectively. In one study, a decreasing trend in the prevalence of fallers was found in participants with 25OHD >40 ng mL −1 compared to those with 25OHD between 20 and 40 ng mL −1 , and compared to those with 25OHD <20 ng mL −1 ( P = 0.033) . Consistently, three cross‐sectional analyses reported an inverse association between the serum concentration of 25OHD and the likelihood of being a faller .…”

“…The 18 studies included in this review are summarized in Table . All studies were published over the last 14 years and were judged to be of good quality using the Newcastle–Ottawa Scale (see Appendix ).…”

“…The number of participants ranged from 80 to 2957 , with a total of 11 to 475 fallers and a prevalence of falls between 11% and 69% . The mean age of studied cohorts ranged between 63 and 86 years , and the proportion of women between 44% and 100% . The serum 25OHD concentration was used as a continuous variable in six studies [] and as a categorical variable (i.e.…”

“…The serum 25OHD concentration was used as a continuous variable in six studies [] and as a categorical variable (i.e. quartiles or threshold values defined a priori ) in five studies; in the remaining seven studies, 25OHD concentration was used as both a continuous and a categorical variable . As shown in Table , different methods were used to determine 25OHD concentrations, the most frequent being radioimmunoassay [].…”

“…Following thorough examination, we excluded 52 of these 70 studies because falls and vitamin D were not study outcomes ( n = 9 and n = 3, respectively), or because the relationship between vitamin D and falls was not examined ( n = 40, including 36 interventional trials that did not provide the vitamin D status at baseline of participants with a history of falls). The remaining 18 studies were included in this review .…”