Rheumatologic diseases in the intensive care unit: epidemiology, clinical approach, management, and outcome

Janssen, Namieta M.; Karnad, Dilip R.; Guntupalli, Kalpalatha K.

doi:10.1016/s0749-0704(02)00025-8

Cited by 85 publications

(88 citation statements)

References 61 publications

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“…[2][3][4][5] Patients with underlying rheumatologic diseases are thought to have a higher mortality than predicted by APACHE II and SAPS II. [6] However, a lower mortality of patients with small-vessel vasculitis admitted to the ICU than predicted by APACHE III has been demonstrated in a recent study. [7] By and large, there are few studies that describe the prognosis and outcome of patients with smallvessel vasculitides in the ICU.…”

Section: Introductionmentioning

confidence: 93%

Outcome of Thirty Patients with ANCA-Associated Renal Vasculitis Admitted to the Intensive Care Unit

et al. 2008

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Section: Introductionmentioning

confidence: 93%

Outcome of Thirty Patients with ANCA-Associated Renal Vasculitis Admitted to the Intensive Care Unit

et al. 2008

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“…The Journal of on May 8, 2018 -Published by www.jrheum.org Downloaded from although these diseases have differing courses and potential causes of ICU admissions 23,24,25,26 . While these studies list worsening of underlying disease as a common reason for ICU admission 23 , patients with RA are most often hospitalized for other systemic medical or surgical conditions or complications from the treatment of RA 22 .…”

Section: Rheumatologymentioning

confidence: 99%

“…While these studies list worsening of underlying disease as a common reason for ICU admission 23 , patients with RA are most often hospitalized for other systemic medical or surgical conditions or complications from the treatment of RA 22 .…”

Section: Rheumatologymentioning

confidence: 99%

“…While hospital mortality has been reported to be higher after ICU admission among persons with all rheumatic diseases compared with the general population 26 , this has not been evaluated in RA specifically. Prior studies of the causes, clinical features, and outcomes of patients with RA requiring ICU admission combined multiple autoimmune rheumatic diseases 23,24,25,26 , making comparisons difficult. We have previously reported a similar increased risk of death following ICU admission in multiple sclerosis and inflammatory bowel disease 35,36 .…”

Section: Peschken Et Al: Critical Illness In Ramentioning

confidence: 99%

“…However, these studies combined multiple autoimmune rheumatic diseases [primarily RA, followed by systemic lupus erythematosus (SLE) and systemic sclerosis] 22,23 ,…”

mentioning

confidence: 99%

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A Population-based Study of Intensive Care Unit Admissions in Rheumatoid Arthritis

Peschken

Hitchon²,

Garland³

et al. 2015

J Rheumatol

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Objective.We aimed to determine the incidence of and mortality after critical illness in rheumatoid arthritis (RA) compared with the general population, and to describe the risks for and characteristics of critical illness in patients with RA.Methods.We used population-based administrative data from the Data Repository at the Manitoba Centre for Health Policy from 1984 to 2010, and linked clinical data from an intensive care unit (ICU) database to identify all persons with RA in the province requiring ICU admission. We identified a population-based control group, matched by age, sex, socioeconomic status, and region of residence. The incidence of ICU admission, reasons for, and mortality after ICU admission were compared between populations using age- and sex-standardized rates, rate ratios, Cox proportional hazards models, and logistic regression models.Results.We identified 10,078 prevalent and 5560 incident cases of RA. After adjustment, the risk for ICU admission was higher for RA (HR 1.65, 95% CI 1.50–1.83) versus the matched general population. From 2000–2010, the annual incidence of ICU admission among prevalent patients was about 1% in RA, with a crude 10-year incidence of 8%. Compared with the general population admitted to ICU, 1 year after ICU admission, mortality was increased by 40% in RA. Cardiovascular disorders were the most common reason for ICU admission in RA.Conclusion.Patients with RA have a higher risk for admission to the ICU than the general population and increased mortality 1 year after admission. Even with advances in management, RA remains a serious disease with significant morbidity.

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Assessment and Management of the Rheumatological Patient in the Critical Care Unit

D’Cruz

Wyncoll²

2011

Autoimmune Diseases

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Rheumatologic diseases in the intensive care unit: epidemiology, clinical approach, management, and outcome

Cited by 85 publications

References 61 publications

Outcome of Thirty Patients with ANCA-Associated Renal Vasculitis Admitted to the Intensive Care Unit

Outcome of Thirty Patients with ANCA-Associated Renal Vasculitis Admitted to the Intensive Care Unit

A Population-based Study of Intensive Care Unit Admissions in Rheumatoid Arthritis

Assessment and Management of the Rheumatological Patient in the Critical Care Unit

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