Rheumatologic complications of HIV infection

Reveille, John D.; Williams, Francis M.

doi:10.1016/j.berh.2006.08.015

Cited by 72 publications

(21 citation statements)

References 81 publications

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“…Different etiologies of arthralgia are frequently found in HIVinfected patient: idiopathic arthralgia, fibromyalgia syndrome, painful articular syndrome, inflammatory arthritis, vasculitis or connective tissue diseases [1,5]. To our knowledge, hand OA in HIV-infected patients has not been reported in the literature.…”

Section: Discussionmentioning

confidence: 87%

Early-developed hand osteoarthritis in treated HIV-positive patients: Four cases

Larcher¹,

Mauboussin²,

Rouanet³

et al. 2015

Joint Bone Spine

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Section: Discussionmentioning

confidence: 87%

Early-developed hand osteoarthritis in treated HIV-positive patients: Four cases

Larcher¹,

Mauboussin²,

Rouanet³

et al. 2015

Joint Bone Spine

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“…In comparing chimpanzee and human immune responses, Sato et al [6] comment on the association of T cell over-reactivity to immune stimuli that results in diseases, such as bronchial asthma, psoriasis, and rheumatoid arthritis. It is interesting that the same HLA antigens identified as important in the development of asthma in HIV-infected patients after HAART and immune reconstitution[1] are also associated with autoimmune diseases, such as psoriasis, psoriatic arthritis, and rheumatoid arthritis that develop in HIV-infected patients following immune reconstitution with HAART [7]. Thus a fundamental immune activation process appears to be operating in these patients that manifests itself as asthma in some patients and as autoimmune disease in others.…”

Section: Introductionmentioning

confidence: 99%

Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents

Siberry

Leister

Jacobson

et al. 2012

Clinical Immunology

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The incidence of asthma and atopic dermatitis (AD) were evaluated in HIV-infected (n=451) compared to HIV-exposed (n=227) but uninfected (HEU) children and adolescents by abstraction from clinical charts. Asthma was more common in HIV-infected compared to HEU children by clinical diagnosis (25% vs. 20%, p = 0.101), by asthma medication use, (31% vs. 22%, p = 0.012), and by clinical diagnosis or both medication use, (34% vs. 25%, p = 0.012). HIV-infected children had a greater risk of asthma compared to HEU children (HR = 1.37, 95% CI: 1.01 to 1.86). AD was more common in HIV-infected than HEU children (20% vs. 12%, p = 0.009)) and children with AD were more likely to have asthma in both cohorts (41% vs. 29%, p = 0.010). HIV-infected children and adolescents in this study had a 30% increased incidence of asthma and AD, a finding critical for millions of HIV-infected children worldwide.

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“…Bones, as well as joints or striated muscle [5][6][7][8] can be affected. Infections may affect peripheral joints, spine, long bones or muscles.…”

Section: Discussionmentioning

confidence: 99%

Musculoskeletal Infections in Human Immunodeficiency Virus

Ntsiba¹,

Ngandeu-Singwe²,

Ondzala³

2012

OJRA

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Objective: To describe clinical, paraclinical and evolution's spectrum of musculoskeletal infections in patients with human immunodeficiency virus. Methods: Descriptive and analytical cross-study carried out on the file of 23.5% presented a musculoskeletal infection among 85 who were infected with human immunodeficiency virus and hospitalized in the Rheumatology Department of Brazzaville Teaching Hospital during 3 years. Results: 7 males and 13 females all HIV/AIDS infected, average age of 35.2 years, range 18 and 68 years. Patients were at C and B stages of CDC Atlanta 1993 classification. We found 7 Pott's diseases, 7 septic arthritis and 6 pyomyositis. Pott's disease affected the lumbar spine in 4 cases, dorsolumbar curve 2 times, dorsal spine once and was complicated by paraplegia in 4 cases. Septic arthritis was exclusively localized at the knee, and myositis was located in the thigh in 3 cases, arm in 2 cases, and buttock in 2 cases, with multifocal localization in 2 cases. The most frequently isolated germ was Staphylococcus aureus; this was isolated 5 times at the knee and thrice in the muscle. The evolution was favorable under antibiotic therapy with recovery periods longer than that in the HIV negative patients. Conclusion: Musculoskeletal infections of HIV related patients have a profile which appears comparable to the immunocompetent patients. Pott's disease affected dorsal and lumbar spine, complicated by paraplegia. Septic arthritis is located on the knee and pyomyositis are frequent with unusual and multifocal localizations. The bacterial ecology is dominated by Staphylococcus aureus and Mycobacterium tuberculosis. The recovery is longer in these patients.

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Rheumatologic complications of HIV infection

Cited by 72 publications

References 81 publications

Early-developed hand osteoarthritis in treated HIV-positive patients: Four cases

Early-developed hand osteoarthritis in treated HIV-positive patients: Four cases

Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents

Musculoskeletal Infections in Human Immunodeficiency Virus

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