Rheumatoid Arthritis in Rheumatological Care of Russia: The Severity of the Disease in a Russian Patient Population: A Cross-Sectional Epidemiological Study (Raiser)

Folomeeva, O M; Folomeyeva, O M; Насонов, Е Л; Андрианова, И. А.; Галушко, Е. А.; Goryachev, D. V.; Dubinina, Tatiana V.; Zhornyak, A P; Krichevskaya, O A; Эрдес, Ш. Ф.

doi:10.14412/1995-4484-2010-1406

Cited by 8 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ГК получали 17-20% анкетированных пациентов с РА из разных реги-онов нашей страны, что согласуется с данными работы C. Klop и соавт. [28], выполненной в рамках валидации алгоритма FRAX ® , где терапия ГК проводилась у 15,6-16,3% больных РА, но значительно меньше, чем было показано в большом отечественном исследовании, в котором установлено, что 65,9% больных РА принима-ли системные ГК [22].…”

Section: Discussionunclassified

“…По данным российского мно-гоцентрового исследования ГЛЮКОСТ, в котором были опрошены 3021 пациент, 47,7% из них имели РА, и 48,7% больных РА принимали пероральные ГК когда-либо в те-чение 3 мес и более [21]. Одномоментное исследование, проведенное в 27 городах России, продемонстрировало, что системное или локальное введение ГК использова-лось у 65,9 и 66,4% пациентов соответственно, а 43% больных принимали ГК внутрь в период проведения ис-следования [22]. Прием ГК приводит к быстрой потере костной массы и повышению риска переломов, особенно в первые месяцы применения.…”

unclassified

See 1 more Smart Citation

The Risk of Osteoporotic Fractures in Patients With Rheumatoid Arthritis: Results of the Program «osteoscreening Russia»

Никитинская¹,

Торопцова²,

Демин³

et al. 2018

rsp

View full text Add to dashboard Cite

Rheumatoid arthritis (RA) and the use of glucocorticoids (GCs) are proven risk factors for osteoporosis (OP) and osteoporotic fractures (OPF). There are also other reasons for increased fracture risk in RA.Objective: to determine the rate of RA in an epidemiological sample of persons aged 50 years and older and to identify those in need of antiosteoporotic therapy among the patients with RA in order to prevent OPF.Subjects and methods. The epidemiological sample included 18,018 people aged 50 years and older (13,941 women and 4,077 men; mean age, 62±10 years). The survey consisted of a unified questionnaire, measurement of daily dietary calcium intake, and calculation of a 10-year fracture risk using the FRAX® algorithm.Results and discussion. The prevalence of RA in the epidemiological population sample aged 50 years and older was 1.7% (1.9% in women and 1.2% in men; p=0.0047). The mean FRAX® values for major OPF in RA patients were significantly higher than those in non-RA individuals: 18.4±10 and 13.2±7.9%, respectively (p=0.0001) for women and 8.9±6.4 and 6.2±3.7%, respectively (p=0.0001) for men. 42% of the patients with RA were at high risk for OPF. Thus, 48% of the women with RA had FRAX® values above the therapeutic intervention threshold; and the non-RA group needed antiosteoporotic therapy significantly less (31%; p=0.00001). At the same time, the detection rate of high-risk OPF in men with and without RA did not differ significantly (8 and 5%, respectively; p>0.05). The most common risk factors (RFs) for OP and OPF in RA patients included previous fractures (33%), secondary causes of OP (30%), GC use (18%), and, additionally, smoking (33%) in male patients with RA. The female patients with RA significantly more frequently took GCs (17%) and had other secondary causes of OP and OPF (33%) than those without RA (7.7% (p=0.0001) and 23% (p=0.0004, respectively). The male patients with RA versus to the population-based control showed significant differences when they only used GCs (20 and 5%, respectively; p = 0.0001); the remaining RFs were encountered at the same frequency. Less than half of the normal daily calcium intake was observed in 20% of men and 16% of women (p=0.53).Conclusion. 42% of the RA patients aged 50 years and older were at high risk for OPF and needed antiosteoporotic therapy. Every third woman with RA had at least one other comorbidity or condition associated with the increased risk of OPF. In the male patients with RA, the FRAX® algorithm could reveal only 8% of persons at high risk for fractures, while 58% of them had two or more additional RFs that can negatively affect bone mineral density and increase the risk of fracture. To identify those who require prevention and treatment of OP and OPF, it is preferable to perform bone densitometry of the axial skeleton among male patients with RA.

show abstract

Section: Discussionunclassified

unclassified

The Risk of Osteoporotic Fractures in Patients With Rheumatoid Arthritis: Results of the Program «osteoscreening Russia»

Никитинская¹,

Торопцова²,

Демин³

et al. 2018

rsp

View full text Add to dashboard Cite

show abstract

“…• данные об инвалидности населения (численность лиц, впервые признанных инвалидами; распределение лиц, впервые признанных инвалидами, по причинам инвалидности; распределение детей, впервые признанных инвалидами в возрасте до 18 лет, по формам болезней; численность С О В P E М Е Н Н А Я Р Е В М А Т О Л О Г И Я № 4 ' 1 9 О Р И Г И Н А Л Ь Н Ы Е И С С Л Е Д О В А Н И Я По некоторым оценкам, в Российской Федерации РА могут страдать от 800 тыс. до 1 млн человек [3,4]. Согласно официальной статистике, в 2016 г. заболеваемость РА в нашей стране составляла 33 232 больных (22,7 на 100 тыс.…”

Section: влияние пр на структуру трудоспособного населенияunclassified

“…В настоящем исследования рассмотрены три нозологические формы -ревматоидный артрит (РА), анкилозирующий спондилит (АС) и псориатический артрит (ПсА), характеризующиеся высокой распространенностью, заболеваемостью и частой инвалидизацией в трудоспособном возрасте 3 .…”

unclassified

“…В ходе данного исследования принимали во внимание, что цифры официальной статистики могут существенно отличаться от результатов независимых международных исследований и экспертных оценок по всем трем нозологическим формам [3,4,6,[8][9][10]. Такое расхождение во многом объясняется поздним обращением пациентов за медицинской помощью и сложностью установления диагноза на поликлиническом этапе, а также несистемным подходом к формированию статистических данных из-за отсутствия федеральных регистров.…”

unclassified

See 1 more Smart Citation

Medical and economic analysis of the impact of rheumatoid disease-associated disability on the country's economy in terms of implementation of pension reforms

Лила¹,

Древаль²,

Инамова³

et al. 2019

Sovremennaâ revmatologiâ

View full text Add to dashboard Cite

The paper presents the data of an original study evaluating the impact of disability associated with a number of rheumatic diseases (RDs) (rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis) on the country's economy, as well as their related losses of the state under the conditions of implementation of the upcoming pension reform (PR). The authors consider the socioeconomic importance of disability associated with RDs in the current period and after PR implementation in 2019–2028, determine the degree of its influence on the country's gross domestic product, and also calculate the economic efficiency of return of the potentially able-bodied proportion of disabled people (able-bodied population) to socioeconomic activity.The opinions of experts and leading experts in this area from different subjects of the Russian Federation were taken into account when preparing the study.

show abstract

Assessment of organization of medical care and drug provision for patients with rheumatic diseases, and the socioeconomic burden of these diseases in the Russian Federation

Лила¹,

Древаль²,

Shipitsyn³

2018

RJTAO

View full text Add to dashboard Cite

This article reviews data on the assessment of the incidence of rheumatoid arthritis (RA), ankylosing spondylitis (AS), and psoriatic arthritis (PsA, arthropathic psoriasis), as well as related disability and the economic burden of these nosological entities, including their therapy with biological agents. It considers the issues of organization and quality of medical care, drug supply, normative and legal regulation. The paper also shows the important epidemiological and socioeconomic importance of RA, AS, and PsA in Russia, points out the regional peculiarities of medical care and drug provision, and proposes solutions for their optimization at the federal and local levels. In preparing this investigation, the authors have taken into account the opinions of many specialists and experts in this field from different subjects of the Russian Federation.

show abstract

Rheumatoid Arthritis in Rheumatological Care of Russia: The Severity of the Disease in a Russian Patient Population: A Cross-Sectional Epidemiological Study (Raiser)

Cited by 8 publications

References 29 publications

The Risk of Osteoporotic Fractures in Patients With Rheumatoid Arthritis: Results of the Program «osteoscreening Russia»

The Risk of Osteoporotic Fractures in Patients With Rheumatoid Arthritis: Results of the Program «osteoscreening Russia»

Medical and economic analysis of the impact of rheumatoid disease-associated disability on the country's economy in terms of implementation of pension reforms

Assessment of organization of medical care and drug provision for patients with rheumatic diseases, and the socioeconomic burden of these diseases in the Russian Federation

Contact Info

Product

Resources

About