Rheumatic manifestations of hematologic disorders

Adult Leukemic Synovitis Is Associated With Leukemia of Monocytic Differentiation

“…In contrast, pediatric patients, particularly those with acute lymphoblastic leukemia, may present with bone and joint pain; however, these cases are predominantly due to periosteal sensitivity secondary to marrow expansion by the neoplastic cells. 1 Leukemic synovitis is defined as joint pain and swelling in association with documented leukemia after other causes have been excluded. Clinically, patients present with inflamed, erythematous, and tender joints.…”

Angeíte isolada do sistema nervoso central em paciente com síndrome mielodisplásica: relato de caso

“…No entanto, a associação entre síndromes mielodisplásicas e vasculites sistêmicas já foi bastante estudada. A ocorrência de fenôme-nos autoimunes não é incomum em pacientes com mielodisplasia, chegando algumas séries a sugerir incidência de cerca de 10%.As manifestações clínicas desses fenômenos podem incluir: vasculites sistêmicas agudas, vasculites cutâneas, febre, artrite, infiltrados pulmonares, glomerulonefrite e ainda doenças clássicas do tecido conectivo como: policondrite relapsante, síndrome de Sjögren e formas atípicas de doença de Behçet 9 .…”

Hemorrhagic Bullae After Cryosurgery in a Patient With Hemophilia A

“…10 Although such patients can bleed at any site, the most common sites are into joints and muscles (approximately 80%) and from the gastrointestinal tract. 11 In contrast, mucosal and cutaneous bleeding is more characteristic of platelet dysfunction or von Willebrand disease. Most patients with hemophilia are diagnosed very early, and thus, the physician performing cryosurgery is aware of the increased risk.…”