Rheumatic manifestations in primary hypothyroidism

Kole, Alakes Kumar; Roy, Rammohan; Kole, Dalia Chanda

doi:10.1016/j.injr.2012.12.005

Cited by 2 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Disproportionate growth and skeletal abnormalities including epiphyseal dysgenesis, delayed maturation and shortening or the vertebral bodies are reported in dogs with congenital hypothyroidism (Greco et al 1991, Saunders & Jezyk 1991, Mooney & Anderson 1993. Rheumatic and musculoskeletal manifestations of hypothyroidism are well documented in the human literature with multiple different myopathies, neuropathies and arthropathies reported (Dorwart & Schumacher 1975, Bland et al 1979, Cakir et al 2003, Tagoe et al 2012, Kole et al 2013. Similar to the dog in this report, a distinct, non-inflammatory arthropathy causing joint effusion has been reported in human hypothyroid patients but based on the literature search, this is the first report of this manifestation in the veterinary literature (Dorwart & Schumacher 1975, Bland et al 1979.…”

Section: Discussionmentioning

confidence: 99%

“…Rheumatic and musculoskeletal conditions associated with hypothyroidism in people include non-specific myalgia and arthralgia, rheumatoid arthritis, fibromyalgia, carpal tunnel syndrome, stenosing tenosynovitis and adhesive capsulitis (Cakir et al 2003, Kole et al 2013. While a direct and causal relationship between hypothyroidism and these conditions cannot always be made, it appears that concurrent rheumatic disease is commonly identified in humans with acquired hypothyroidism with one study reporting concurrent rheumatic conditions in 62% of hypothyroid patients (Soy et al 2006).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Non‐inflammatory joint effusions as a presenting sign of hypothyroidism in a dog

Kelly

Quinn

2021

J of Small Animal Practice

View full text Add to dashboard Cite

Non-inflammatory joint effusion with characteristically increased synovial fluid viscosity is a rare but well-recognised rheumatic manifestation of hypothyroidism in people and based on the literature search, this is the first report of the condition in dogs. A 2-year-old Pyrenean Mountain dog presented for lameness and multiple joint effusions. CT confirmed effusions affecting multiple limb joints along with delayed closure of multiple physes. Synovial fluid analysis from the effused joints showed no evidence of inflammation but the fluid viscosity was markedly increased. Serum total thyroxine concentration was decreased, thyroid-stimulating hormone concentration was increased and antithyroglobulin autoantibody measurement returned a positive result. Oral levothyroxine supplementation resulted in relatively rapid and complete resolution of the clinical signs, in association with attaining a euthyroid state. Follow-up examination and CT six months later confirmed resolution of the joint effusions and significant improvement or resolution of the other documented skeletal changes.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Non‐inflammatory joint effusions as a presenting sign of hypothyroidism in a dog

Kelly

Quinn

2021

J of Small Animal Practice

View full text Add to dashboard Cite

show abstract

“…18 One study has shown around 50% of participants who had hypothyroidism was suffering from back pain which may point towards a causal association. 19 LBP can often be seen in women with menstrual irregularities although a definitive association has not been established yet. 20 In a study by Serranheira F et al suggests that there is an association between demanding jobs that need high physical exertion, LBP and sickness leave from work.…”

Section: Introductionmentioning

confidence: 99%

Variations in anthropometry and physical characteristics of staff with low back pain working in tertiary hospital

Varkey

Philipose

2021

Int J Res Orthop

View full text Add to dashboard Cite

Background: Several links were searched to know the variations in anthropometry and physical characteristics of staff with low back pain (LBP) working in tertiary hospital. Controversy exists between the association of these characteristics with LBP. The study was conducted to understand the relation between physical characteristics and LBP in the south Indian population.Methods: Ethical approval was obtained from the institutional health research ethical committee. A survey was conducted using a proforma and it was circulated among the staff and doctors in the tertiary care hospital. The validated questionnaires were framed to collect all the physical characteristics and anthropometry of the respondents and history of LBP. The distribution of the parameters are calculated either as mean±two standard deviation, or as count and percentage. The tests used for comparison is the t test and for association is the chi square (𝛘2) test. A p value less than or equal to 0.5 is considered as statistically significant. The data was analysed using the microsoft excel and the minitab (17) software.Results: The study showed significant positive association of back pain with increase in weight of the subjects, history of back trauma, spinal injections and lifting heavy weights (p value<0.01). There was no significant association of LBA with variables like history of menstrual irregularities and mode of transport.Conclusions: There is a positive association between LBP with anthropometric features like weight of the patient and also physical characteristics like history of back trauma, spinal injections and lifting heavy weights.

show abstract

Rheumatic manifestations in primary hypothyroidism

Cited by 2 publications

References 17 publications

Non‐inflammatory joint effusions as a presenting sign of hypothyroidism in a dog

Non‐inflammatory joint effusions as a presenting sign of hypothyroidism in a dog

Variations in anthropometry and physical characteristics of staff with low back pain working in tertiary hospital

Contact Info

Product

Resources

About