Rheological insights on Carboxymethyl cellulose hydrogels

Enoch, Karolinekersin; Somasundaram, Anbumozhi Angayarkanni

doi:10.1016/j.ijbiomac.2023.127481

Cited by 11 publications

(4 citation statements)

References 112 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…63 It is noteworthy that Enoch et al found that an increase in the concentration of CMC could enhance the storage modulus of the hydrogel, making it harder and more stable. 58 This was attributed to the increase in hydrogen bonds within the polymer network with the elevated concentration of CMC.…”

Section: Resultsmentioning

confidence: 99%

“…These findings suggested structural transitions and damage within the hydrogel polymer network. 58 Following the crossover point, the hydrogel loses its gel-like properties, transitioning into a sol state and becoming non-deformable. 59,60 Moreover, when the hydrogel was subjected to strains ranging between 10–100%, G ′ remained greater than G ′′ (Fig.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

l-Carnosine loaded on carboxymethyl cellulose hydrogels for promoting wound healing

Zhang,

Li,

Chen

et al. 2024

RSC Adv.

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

l-Carnosine loaded on carboxymethyl cellulose hydrogels for promoting wound healing

Zhang,

Li,

Chen

et al. 2024

RSC Adv.

View full text Add to dashboard Cite

show abstract

“…One of the most commonly used stiffness measurement techniques for biomaterials or synthetic materials in biomedical research is shear rheometry. Based on shear stress or shear strain, rheological measurements can range from pascal to megapascal levels. − Mechanical characterization techniques and the associated measure(s) of stiffness commonly employed in matrix stiffness literature are presented (Table ).…”

Section: Extracellular Matrixmentioning

confidence: 99%

Exploiting Matrix Stiffness to Overcome Drug Resistance

Aydin,

Ozcelikkale,

Acar

2024

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

Drug resistance is arguably one of the biggest challenges facing cancer research today. Understanding the underlying mechanisms of drug resistance in tumor progression and metastasis are essential in developing better treatment modalities. Given the matrix stiffness affecting the mechanotransduction capabilities of cancer cells, characterization of the related signal transduction pathways can provide a better understanding for developing novel therapeutic strategies. In this review, we aimed to summarize the recent advancements in tumor matrix biology in parallel to therapeutic approaches targeting matrix stiffness and its consequences in cellular processes in tumor progression and metastasis. The cellular processes governed by signal transduction pathways and their aberrant activation may result in activating the epithelial-tomesenchymal transition, cancer stemness, and autophagy, which can be attributed to drug resistance. Developing therapeutic strategies to target these cellular processes in cancer biology will offer novel therapeutic approaches to tailor better personalized treatment modalities for clinical studies.

show abstract

“…This anionic cellulose water-soluble derivative has a wide range of applications [12,13] in food [14], textiles [15,16], pharmaceutical engineering [17], biomedical engineering [18], energy storage [19], and other fields due to its unique surface properties, biological adaptability, adjustable hydrophilicity, low cost, and abundant raw material sources. Due to its abundant hydroxyl groups, CMC can serve as a hydrogen bonding site, and its anionic polyelectrolyte properties can provide long-range electrostatic interactions, providing reliable cohesion and adhesion for CMC as an adhesive [20][21][22][23]. Meanwhile, the excellent water absorption ability of CMC can maintain excess water when used as a binder [24].…”

Section: Introductionmentioning

confidence: 99%

A Novel Nanofiber Hydrogel Adhesive Based on Carboxymethyl Cellulose Modified by Adenine and Thymine

Xie,

Yang,

Wan

et al. 2024

Polymers

View full text Add to dashboard Cite

Natural polymer-based adhesive hydrogels have garnered significant interest for their outstanding strength and versatile applications, in addition to being eco-friendly. However, the adhesive capabilities of purely natural products are suboptimal, which hampers their practical use. To address this, we engineered carboxymethyl cellulose (CMC) surfaces with complementary bases, adenine (A) and thymine (T), to facilitate the self-assembly of adhesive hydrogels (CMC-AT) with a nanofiber configuration. Impressively, the shear adhesive strength reached up to 6.49 MPa with a mere 2% adhesive concentration. Building upon this innovation, we conducted a comparative analysis of the shear adhesion properties between CMC and CMC-AT hydrogel adhesives when applied to delignified and non-delignified wood chips. We examined the interplay between the adhesives and the substrate, as well as the role of mechanical interlocking in overall adhesion performance. Our findings offer a fresh perspective on the development of new biodegradable polymer hydrogel adhesives.

show abstract

Rheological insights on Carboxymethyl cellulose hydrogels

Cited by 11 publications

References 112 publications

l-Carnosine loaded on carboxymethyl cellulose hydrogels for promoting wound healing

l-Carnosine loaded on carboxymethyl cellulose hydrogels for promoting wound healing

Exploiting Matrix Stiffness to Overcome Drug Resistance

A Novel Nanofiber Hydrogel Adhesive Based on Carboxymethyl Cellulose Modified by Adenine and Thymine

Contact Info

Product

Resources

About