“…Hydroxypropyl methylcellulose (HPMC), a derivative of cellulose, the richest natural polymer on the Earth, has good water solubility and biodegradability, and excellent film-forming, mechanical and barrier properties. Therefore, HPMC has been extensively used in food packaging, medicinal capsules, and other drug delivery systems (Imran et al, 2014;Zhang et al, 2017a;Zhang et al, 2015;Zhang et al, 2017b). However, the high prices of HPMC limit its general applications, even for use in therapeutic delivery systems (Wang et al, 2016a;Wang et al, 2016b;Zhang et al, 2013b;Zhang et al, 2013c).…”