Rhabdoviruses: Rabies

Tordo, Noël; Ceccaldi, Pierre‐Emmanuel; Gaudin, Yves; Wandeler, A. I.

doi:10.1002/9780470688618.taw0257

Cited by 2 publications

(2 citation statements)

References 345 publications

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“…In addition, most of the phytoviruses that multiply in insect vectors and are transmitted through the circulative mode are classified in families that also contain animal viruses. This is true for family Reoviridae , which includes rotavirus, a major cause of gastroenteritis in humans [ 36 ], family Rhabdoviridae , which notably includes rabies virus [ 37 ], and family Bunyaviridae , which encompasses human pathogens such as Hantaan virus and Toscana virus [ 38 , 39 , 40 ]. Within the family Rhabdoviridae , genomic organization indicates that some plant viruses of genera Nucleorhabdovirus and Cytorhabdoviru s differ from animal viruses of genera Vesiculovirus , Lyssavirus , Novirhabdovirus and Ephemerovirus only by the presence of an additional gene coding for a movement protein, a protein essential for the systemic spread of the virus in the host plant [ 17 , 18 , 37 , 41 ].…”

Section: Close Relatedness Between Plant and Animal Viruses And Evmentioning

confidence: 99%

Can Plant Viruses Cross the Kingdom Border and Be Pathogenic to Humans?

Balique

Lecoq²,

Raoult

et al. 2015

Viruses

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Phytoviruses are highly prevalent in plants worldwide, including vegetables and fruits. Humans, and more generally animals, are exposed daily to these viruses, among which several are extremely stable. It is currently accepted that a strict separation exists between plant and vertebrate viruses regarding their host range and pathogenicity, and plant viruses are believed to infect only plants. Accordingly, plant viruses are not considered to present potential pathogenicity to humans and other vertebrates. Notwithstanding these beliefs, there are many examples where phytoviruses circulate and propagate in insect vectors. Several issues are raised here that question if plant viruses might further cross the kingdom barrier to cause diseases in humans. Indeed, there is close relatedness between some plant and animal viruses, and almost identical gene repertoires. Moreover, plant viruses can be detected in non-human mammals and humans samples, and there are evidence of immune responses to plant viruses in invertebrates, non-human vertebrates and humans, and of the entry of plant viruses or their genomes into non-human mammal cells and bodies after experimental exposure. Overall, the question raised here is unresolved, and several data prompt the additional extensive study of the interactions between phytoviruses and non-human mammals and humans, and the potential of these viruses to cause diseases in humans.

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Section: Close Relatedness Between Plant and Animal Viruses And Evmentioning

confidence: 99%

Can Plant Viruses Cross the Kingdom Border and Be Pathogenic to Humans?

Balique

Lecoq²,

Raoult

et al. 2015

Viruses

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“…Rabies is a contagious zoonosis caused by a neurotropic virus that acts on the Central Nervous System (CNS). The virus produces an acute and deadly encephalomyelitis because its replication leads to nervous system cell destruction 1 . The virus often causes behavioural and motor alterations, including restlessness, rage, aggressiveness and hind limb paralysis 2 .…”

Section: Introductionmentioning

confidence: 99%

Medula cervical como material para diagnóstico laboratorial da Raiva

Rolim,

Teixeira,

Costa

et al. 2009

Rev Inst Adolfo Lutz

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A Raiva é uma zoonose neurotrópica infecto-contagiosa, cuja persistência está associada: aos cães abandonados nas ruas, baixa imunidade, reduzida procura pelo diagnóstico laboratorial devido a difícil coleta e transporte do material (cérebro). Portanto, justifica-se o estudo da medula cervical (SNC), por ser via obrigatória dos vírus rábicos para o cérebro e deste para todo corpo, cuja anatomia e localização, facilitam a coleta. Assim, objetivou-se testar sua eficácia como material para o diagnóstico laboratorial da Raiva. Para tanto, inoculou-se vírus da raiva intramuscular em cinco Rattus. Após o óbito, o cérebro e a medula cervical de cada animal foram macerados e inoculados intracerebral em cinco Rattus (repetições). Os 25cérebros e 25 medulas foram 100% positivo para Raiva, pelas provas de imunofluorescência e inoculação intracerebral. Apesar da concordância entre o cérebro e a medula cervical, este estudo propõe a utilização da medula cervical como material para o diagnóstico laboratorial da Raiva.

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Rhabdoviruses: Rabies

Cited by 2 publications

References 345 publications

Can Plant Viruses Cross the Kingdom Border and Be Pathogenic to Humans?

Can Plant Viruses Cross the Kingdom Border and Be Pathogenic to Humans?

Medula cervical como material para diagnóstico laboratorial da Raiva

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