Rhabdoviridae, Rabies Virus

Ogino, Tomoaki

doi:10.1016/b978-0-12-818731-9.00051-3

Cited by 1 publication

(2 citation statements)

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“…78 RABV is mostly spread to humans via the rabid dog's saliva when biting humans, this virus penetrates the motor neurons by clathrin endocytosis mechanism, mRNAs of RABV possess a five-prime cap as well as polyadenylated tail by strategies carried out through its multi-role RNA polymerase. 79 Rabies disease is noted as fatal, it targets the nervous system, and it is neurotropic, firstly, binding to Nicotinic acetylcholine receptor (nAChR) at special synapse located among motor neuron end and muscle fibre. It goes through the axons of peripheral nerves directly to the Central Nervous System (CNS).…”

Section: Rabies Virusmentioning

confidence: 99%

“…When talking about replication, the special thing in RABV is that the replication goes asymmetrically, replication produces around a fifty‐fold excess ratio between genomes over anti‐genomes 78 . RABV is mostly spread to humans via the rabid dog's saliva when biting humans, this virus penetrates the motor neurons by clathrin endocytosis mechanism, mRNAs of RABV possess a five‐prime cap as well as poly‐adenylated tail by strategies carried out through its multi‐role RNA polymerase 79 …”

Section: Rabies Virusmentioning

confidence: 99%

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Rodent‐borne viruses in the region of Middle East

AL-Eitan

Alnemri

Alkhawaldeh

et al. 2023

Reviews in Medical Virology

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Rodents are one of the most abundant mammal species in the world. They form more than two‐fifth of all mammal species and there are approximately 4600 existing rodent species. Rodents are capable of transmitting deadly diseases, especially those that are caused by viruses. Viruses and their consequences have plagued the world for the last two centuries, three pandemics occurred during the last century only. The Middle East is situated at the crossroads of Africa and Asia, along with the Mediterranean Sea and the Indian Ocean, its geographic importance is gained through the diversity of topographies, biosphere, as well as climate aspects that make the region vulnerable to host emerging diseases. Refugee crises also play a major role in expected epidemic outbreaks in the region. Public health has always been the most important priority, and our aim in this review is to raise awareness among public health organisations across the Middle East about the dangers of rodent borne diseases that have been reported or are suspected to be found in the region.

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Section: Rabies Virusmentioning

confidence: 99%

Section: Rabies Virusmentioning

confidence: 99%