Rhabdomyosarcoma: A clinicopathological study and classification of 39 cases

Horn, Robert C.; Enterline, Horatio T.

doi:10.1002/1097-0142(195801/02)11:1<181::aid-cncr2820110130>3.0.co;2-i

Cited by 515 publications

(122 citation statements)

References 15 publications

Supporting

Mentioning

108

Contrasting

Unclassified

Order By: Relevance

“…The standard classification is still the one proposed by Horn and Enterline [7] in 1958 which divided the tumor into four subgroups: embryonal, alveolar, botryoid and pleomorphic and noted that botryoid was actually a subtype of embryonal [6]. There seems to be a discrete age range characterizing RMS, so that embryonal types occur in infants and toddlers, pleomorphic types arise in adults, and alveolar tumors seem to affect all age groups.…”

Section: Discussionsupporting

confidence: 88%

Primary Intra-Abdominal Rhabdomyosarcoma in an Adult: an Unusual Presentation and Review of Literature

Yadav

Sinha

Ahmed

et al. 2015

Indian J Surg Oncol

View full text Add to dashboard Cite

Rhabdomyosarcomas, the commonest soft tissue sarcoma in paediatric age group, represent 5-10 % of all solid tumors in childhood. These tumors are rare in adult population. There are sporadic case reports of intra-abdominal rhabdomyosarcoma, but mostly in paediatric age group. Here we are reporting an unsual case of intra abdominal rhabdomyosarcoma in an elderly which presented with acute intestinal obstruction. CECT abdomen showed a solid mass in retroperitoneum compressing adjacent bowel loops. Upon emergency exploratory laparotomy a hard mass was found to be compressing the ascending colon and infiltrating into duodenum, pancreas and liver. No specific organ of origin could be identified. Biopsy was taken, as the mass was unresectable and ileostomy was done. Histopthological examination revealed embryonal rhabdomyosarcoma. Rarity of this disease and unusual presentation prompted us to report this case.

show abstract

Section: Discussionsupporting

confidence: 88%

Primary Intra-Abdominal Rhabdomyosarcoma in an Adult: an Unusual Presentation and Review of Literature

Yadav

Sinha

Ahmed

et al. 2015

Indian J Surg Oncol

View full text Add to dashboard Cite

show abstract

“…Drawing from the key reports described above and using their own series of 39 cases, in 1958, Horn and Enterline (20) derived the first commonly used subclassification system for rhabdomyosarcomas (Table 1). This system came into common use in the latter part of the 1900s and appeared to work well from a clinicopathologic standpoint, as it predictably defined tumor types likely to occur in given age ranges and anatomic sites.…”

Section: Standard Classificationmentioning

confidence: 99%

Pathologic Classification of Rhabdomyosarcomas and Correlations with Molecular Studies

2001

View full text Add to dashboard Cite

Rhabdomyosarcoma, the most common soft-tissue malignancy of childhood and adolescence, comprises a group of differing pathobiologic entities linked by their common propensity for formation of neoplastic skeletal muscle, a feature that results from biological forces related to aberrant transcription signals and the resultant production of myogenic proteins. At a molecular level, however, rhabdomyosarcomas form a heterogeneous group that can be subdivided into distinct clinicopathologic entities based on morphologic appearance and genetic makeup. These differing morphologic features were recognized in the mid-1900s by Horn and Enterline with their division of rhabdomyosarcomas into embryonal, alveolar, botryoid, and pleomorphic subtypes. More recent histologic and biologic studies have resulted in description of additional entities, such as spindle cell and anaplastic rhabdomyosarcoma, and refinements in recognition of the original entities, such as solid-alveolar rhabdomyosarcoma. Familiarity with newer classifications and their relationship to molecular aberrations is key to stratifying patients on current therapeutic protocols and proposed innovative genetic therapies.

show abstract

“…The Intergroup Rhabdomyosarcoma Studies (IRS) Committee and World Health Organization recognize the embryonal (with botryoid variant), alveolar and pleomorphic subtypes of RMS [9,10] . Accounting for 60% of all cases, embryonal rhabdomyosarcoma is the most frequent form to originate in the head and neck.…”

Section: Discussionmentioning

confidence: 99%

Rhabdomyosarcoma of nose, nasopharynx and paranasal sinuses

Mondal

Pal

Misra

et al. 2009

Indian J Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

Rhabdomyosarcoma is an aggressive malignant soft tissue tumor that arises from primitive striated muscle cells called rhabdomyoblasts. It is the most common soft tissue malignant tumor in children and accounts for about 7-8% of childhood cancers. It can arise from almost anywhere in the body but it is most common in the head and neck region. This article presents six cases of rhabdomyosarcoma involving the nose, nasopharynx and the paranasal sinuses four of which were treated with a combination of radiotherapy and chemotherapy and two were treated with medial maxillectomy combined with chemotherapy and radiotherapy.

show abstract

Rhabdomyosarcoma: A clinicopathological study and classification of 39 cases

Cited by 515 publications

References 15 publications

Primary Intra-Abdominal Rhabdomyosarcoma in an Adult: an Unusual Presentation and Review of Literature

Primary Intra-Abdominal Rhabdomyosarcoma in an Adult: an Unusual Presentation and Review of Literature

Pathologic Classification of Rhabdomyosarcomas and Correlations with Molecular Studies

Rhabdomyosarcoma of nose, nasopharynx and paranasal sinuses

Contact Info

Product

Resources

About