Rhabdomyolysis associated with Mycoplasma pneumoniae infection

Sertoğullarından, Bünyamin; Özbay, Mustafa Bilal; Ertem, Furkan U.; Milanlıoğlu, Aysel; Durán, M. Gómez; Özbay, Bülent; Aslan, Mehmet

doi:10.20452/pamw.1597

Cited by 4 publications

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“…Rhabdomyolysis has been associated with a variety of viral and bacterial infections. The common reported acute viral infection associated with rhabdomyolysis include influenza, parainfluenza, Epstein-Barr virus, Cytomegalic virus, Herpes Simplex virus, and Human Immunodeficiency Virus as well as other respiratory tract pathogens [7][8][9][10][11][12].…”

Section: Discussionmentioning

confidence: 99%

Weakness and elevated creatinine kinase as the initial presentation of coronavirus disease 2019 (COVID-19)

Chan

Farouji

Hanoud

et al. 2020

The American Journal of Emergency Medicine

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COVID-19 is a global public health emergency with more than one million positive cases across the globe. COVID-19 has a multifaceted presentation. We are herein to report two cases of SARS-CoV-2 induced rhabdomyolysis with an initial presentation of weakness and elevated creatinine kinase (CK). Both patients had no respiratory symptoms, they only complained of generalized weakness and were found to have elevated CK. Routine chest X-ray showed bilateral infiltrates in both cases and subsequently reverse-transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2 was positive. To the best of our knowledge, there was only one literature to date documented SARS-CoV-2 induced rhabdomyolysis as a late complication of COVID-19 patient. Our cases showed that elevated CK and rhabdomyolysis can be the sole initial presentation of patients with COVID-19 and total CK should be ordered in every patient on admission.

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Section: Discussionmentioning

confidence: 99%

Weakness and elevated creatinine kinase as the initial presentation of coronavirus disease 2019 (COVID-19)

Chan

Farouji

Hanoud

et al. 2020

The American Journal of Emergency Medicine

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“… Reference: [ 6 , 10 , 11 ]; [ 3 , 12 ] E. coli Escherichia coli, SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2, HIV Human immunodeficiency virus …”

Section: Discussionmentioning

confidence: 99%

Legionella associated rhabdomyolysis: a case report

Bavishi

Jain

2023

J Med Case Reports

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Background Infections have been recognized as an uncommon cause of rhabdomyolysis, with evidence indicating a worse prognosis when compared to rhabdomyolysis caused by other etiologies. Diseases caused by Legionella pneumophila can present variably, ranging from mild to severe illness, as is sometimes the case with pneumonia. In particular, the triad of Legionnaire’s disease, rhabdomyolysis, and acute kidney injury is associated with a significant increase in the morbidity and mortality, with most patients requiring initiation of renal replacement therapy such as hemodialysis. While the exact mechanism of both the muscle and kidney injury in this setting remains unknown, several hypotheses exist, with some research suggesting multiple yet distinct processes occurring in both target organs. Case presentation In this case report, we describe a 53-year-old African American man who presented with Legionella pneumophila pneumonia complicated by rhabdomyolysis and acute kidney injury. He was treated with aggressive fluid resuscitation and a 2-week course of azithromycin. His clinical status improved without necessitating renal replacement therapy or mechanical ventilation. We postulate that early recognition and treatment were key to his recovery. He was discharged 10 days later without recurrence of rhabdomyolysis at the time of this report. Conclusion While there are several well-established and more common causes of rhabdomyolysis, clinicians should recognize Legionella sp. as an etiology, given its association with significant morbidity and mortality.

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Rhabdomyolysis: An Unusual Presentation of Mycoplasma pneumoniae Infection in an Adult—A Case Report and Literature Review

Kaler

Mukhtar

Khan

et al. 2018

Case Reports in Medicine

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Mycoplasma pneumoniae is a common cause of community-acquired pneumonia, and many extrapulmonary manifestations have been described, but rhabdomyolysis is infrequently reported in adults. Of the few cases that have been reported in adults, it was almost exclusively seen when pneumonia was present. We report a case of a 30-year-old male who came in with complaints of fever and myalgia for three days. Immunoglobulin M antibodies for Mycoplasma pneumoniae were positive and trending up, despite having no radiographic evidence of pneumonia on chest X-ray or CT scan. He was treated successfully with levofloxacin and intravenous hydration. Later, his condition was clinically and biochemically improved, and he was discharged. Our patient did not present with typical respiratory tract symptoms of a mycoplasma infection. In addition, there was an absence of pneumonia on imaging, suggesting that rhabdomyolysis secondary to mycoplasma might be underdiagnosed and go untreated in the setting of low clinical suspicion. Upon review of the literature, there is only one other case of mycoplasma infection where rhabdomyolysis occurred in the absence of pneumonia. However, the degree of rhabdomyolysis in our case was much more severe. Although rare, when faced with rhabdomyolysis, Mycoplasma pneumoniae should be kept as a differential diagnosis even in the absence of pneumonia on radiological imaging.

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Rhabdomyolysis associated with Mycoplasma pneumoniae infection

Cited by 4 publications

References 0 publications

Weakness and elevated creatinine kinase as the initial presentation of coronavirus disease 2019 (COVID-19)

Weakness and elevated creatinine kinase as the initial presentation of coronavirus disease 2019 (COVID-19)

Legionella associated rhabdomyolysis: a case report

Rhabdomyolysis: An Unusual Presentation of Mycoplasma pneumoniae Infection in an Adult—A Case Report and Literature Review

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