“…ARF is the most commonly recognized cause of morbidity and mortality in patients with rhabdomyolysis, and myoglobinuric renal fail ure accounts for 5 to 8% of all cases of ARF (2). The major causes of rhabdomyolyis include trauma, ischémie muscle injury, thermal muscle injury, exposure to drugs and toxins, and extreme muscular activity (2,11). The most commonly proposed theories explaining the development of ARF in patients with rhabdomyolysis are direct nephrotoxicity of components of myoglobin, alteration of renal blood flow, and tubular obstruction secondary to precipitation of myo globin, protein, and uric acid crystals (2,(9)(10)(11).…”