“…More specifically, we focus our discussion on the several major factors that impact the performance of implantable BioMEMS devices, namely, (i) drug reservoir size and loading volume [13,14], (ii) effective delivery method, (iii) operating time [15,16], (iv) controllability of the device [1] and (v) biocompatibility of the device [17]. Depending on the specific biological applications, the device must be carefully tailored for the personalized medicine used.…”