Rey auditory-verbal learning test: Structure analysis

Vakil, Eli; Blachstein, Haya

doi:10.1002/1097-4679(199311)49:6<883::aid-jclp2270490616>3.0.co;2-6

Cited by 180 publications

(126 citation statements)

References 21 publications

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“…We tested verbal memory with a modified version of the classical Auditory Verbal Learning Test (Vakil and Blachstein, 1993), which originally comprises 15 words that are presented verbally three times in the present study. Under normal circumstances subjects remember more words after each trial.…”

Section: Assessment Of Episodic Memorymentioning

confidence: 76%

Acute Effects of the Ampakine Farampator on Memory and Information Processing in Healthy Elderly Volunteers

Wezenberg

Verkes

Ruigt³

et al. 2006

Neuropsychopharmacol

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Ampakines act as positive allosteric modulators of AMPA-type glutamate receptors and facilitate hippocampal long-term potentiation (LTP), a mechanism associated with memory storage and consolidation. The present study investigated the acute effects of farampator, 1-(benzofurazan-5-ylcarbonyl) piperidine, on memory and information processes in healthy elderly volunteers. A double-blind, placebocontrolled, randomized, cross-over study was performed in 16 healthy, elderly volunteers (eight male, eight female; mean age 66.1, SD 4.5 years). All subjects received farampator (500 mg) and placebo. Testing took place 1 h after drug intake, which was around T max for farampator. Subjects performed tasks assessing episodic memory (wordlist learning and picture memory), working and short-term memory (N-back, symbol recall) and motor learning (maze task, pursuit rotor). Information processing was assessed with a tangled lines task, the symbol digit substitution test (SDST) and the continuous trail making test (CTMT). Farampator (500 mg) unequivocally improved short-term memory but appeared to impair episodic memory. Furthermore, it tended to decrease the number of switching errors in the CTMT. Drug-induced side effects (SEs) included headache, somnolence and nausea. Subjects with SEs had significantly higher plasma levels of farampator than subjects without SEs. Additional analyses revealed that in the farampator condition the group without SEs showed a significantly superior memory performance relative to the group with SEs. The positive results on short-term memory and the favorable trends in the trail making test (CTMT) are interesting in view of the development of ampakines in the treatment of Alzheimer's disease and schizophrenia.

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Section: Assessment Of Episodic Memorymentioning

confidence: 76%

Acute Effects of the Ampakine Farampator on Memory and Information Processing in Healthy Elderly Volunteers

Wezenberg

Verkes

Ruigt³

et al. 2006

Neuropsychopharmacol

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“…The Rey Auditory Verbal Learning Test (AVLT) (Lezak 1983;Vakil and Blachstein 1993) seems to be an ideal tool to aid in clarifying the effect of late-life insomnia on various episodic memory processes. The Rey AVLT test is widely used for clinical and research purposes (Vakil and Blachstein 1997).…”

Section: Methodsmentioning

confidence: 99%

Association between memory impairment and insomnia among older adults

Haimov

2006

Eur J Ageing

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Chronic insomnia and memory impairment are both common complaints among older adults. Even so, only a few studies to date have examined the effects of chronic insomnia on memory processes among older people, and the results of these studies are contradictory. Therefore, in the current study we examined whether late-life insomnia is associated with the memory status of older adults. The study population comprised two groups: 50 older adult subjects without sleep disorders, and 23 older adult insomniacs. Memory processing for each of the two groups was evaluated using the Rey Auditory Verbal Learning Test (AVLT). The results demonstrate that chronic insomnia in older adults is associated with impairment in memory. Specifically, we found that older people suffering from late-life insomnia exhibit significantly reduced performance in learning rate and in temporal order judgment as well as significantly reduced resistance to proactive interference. The present findings suggest that late-life insomnia may be one of the factors contributing to the decline in memory processing seen among older people.

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“…regarding learning analyses, the method developed by Ivnik et al 10 in MoANs (Mayo's older Americans Normative studies) was employed, which standardizes scoring as follows: Total Learning (TL): total learning is established by summing up words recalled over the five trials; Learning over Trials (LoT): calculated based on TL, adjusted for the first trial, that is, LoT = TL -(5 × number of words obtained in the first trial). The rAVLT assesses a range of cognitive skills such as attention, different components of working memory and learning [10][11][12][13] .…”

Section: Ravltmentioning

confidence: 99%

“…The rAVLT assesses a range of cognitive skills such as attention, different components of working memory and learning [10][11][12][13] . Statistical analysis differences amongst means for continuous data were tested using parametric as well as their corresponding non-parametric tests, which without exception produced similar results.…”

Section: Ravltmentioning

confidence: 99%

The relationship between working memory and apraxia of speech

Martins

Ortiz

2009

Arq. Neuro-Psiquiatr.

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-The present study aimed to verify the relationship between working memory (WM) and apraxia of speech and explored which WM components were involved in the motor planning of speech. A total of 22 patients and 22 healthy adults were studied. These patients were selected according to the following inclusion criteria: a single brain lesion in the left hemisphere, presence of apraxia of speech and sufficient oral comprehension. This study involved assessment of apraxia of speech and evaluation of working memory capacity. The performance of apraxic patients was significantly poorer than that of controls, where this reached statistical significance. The study concluded that participants with apraxia of speech presented a working memory deficit and that this was probably related to the articulatory process of the phonoarticulatory loop. Furthermore, all apraxic patients presented a compromise in working memory.Key Words: memory, working memory, speech production, motor planning of speech, apraxia, apraxia of speech.a interrelação entre memória operacional e apraxia de fala resumo -o objetivo do presente estudo foi verificar a interrelação entre memória operacional e apraxia verbal e explorar quais os componentes desta memória estariam envolvidos na programação motora da fala. Foram avaliados 22 pacientes apráxicos e 22 controles. Todos os participantes foram submetidos a avaliação da apraxia de fala. Para investigar a memória operacional, foram aplicados o teste de span de dígitos na ordem direta e inversa, um teste de repetição de palavras longas e curtas e o Rey Auditory Verbal Learning Test, que investiga, além da alça articulatória, o buffer episódico. o desempenho dos apráxicos em todos os testes de memória foi estatisticamente significante mais baixo que o desempenho dos controles. Concluímos que indivíduos com apraxia apresentam um déficit na memória operacional e que este déficit está mais relacionado ao processo articulatório da alça fonoarticulatória.PALAVrAs-CHAVe: memória, memória operacional, programação motora da fala, apraxia, apraxia verbal. The first and most-used definition of working memory (WM) was devised by Allan Baddeley 1 who conceived this as a system enabling temporary storage and manipulation of information required to carry out the complex activities of language processing, learning and reasoning. In 2000, Baddeley 2 made the final additions to the WM model which currently encompasses the central executive, visuo-spatial sketchpad, phonoarticulatory loops, and episodic buffer. The phonoarticulatory loop may be divided into the phonological store and articulatory process. The former involves storage of all material from auditory code while the latter is responsible for temporary holding of this material in the memory allowing subsequent retrieval 3 . studies have shown that WM span may vary and that factors such as phonemic similarity and word length can influence memory processing [3][4][5] . It was also investigated the capacity of WM during impeded retention of auditory informatio...

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Rey auditory-verbal learning test: Structure analysis

Cited by 180 publications

References 21 publications

Acute Effects of the Ampakine Farampator on Memory and Information Processing in Healthy Elderly Volunteers

Acute Effects of the Ampakine Farampator on Memory and Information Processing in Healthy Elderly Volunteers

Association between memory impairment and insomnia among older adults

The relationship between working memory and apraxia of speech

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