Revolutionizing C–H Activation Reactions: Harnessing Green Solvents for Sustainable Catalysis

Abstract

This review deals with the developing field of C–H activation reactions and particularly focuses on green catalysis through the use of environmentally friendly solvents. It evaluates the effects of these solvents on reactions outcomes, environmental aspects and general efficacy pointing out their advantages lead to greater selectivity, lower level of toxicity and enhanced reaction rates. Water and biobased alternatives such as Polyethylene glycols, Ethanol, Gamma-valerolactone, Methanol, p-cymene or 2-methyltetrahydrofurane, Glycerol or Di ethyl carbonate represent representative examples of such solvents. Its scope encompasses the study of different methodologies, catalysts, and reaction conditions that help to develop C–H activation reactions with green solvents.